WormBase Tree Display for Gene: WBGene00006948
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| WBGene00006948 | SMap | S_parent | Sequence | F52E4 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | wrt-2 | Person_evidence | WBPerson83 | |||||
| Sequence_name | F52E4.6 | ||||||||
| Molecular_name | F52E4.6 | ||||||||
| F52E4.6.1 | |||||||||
| CE07273 | |||||||||
| Other_name | CELE_F52E4.6 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | wrt-2 | ||||||||
| DB_info | Database | AceView | gene | XD712 | |||||
| WormQTL | gene | WBGene00006948 | |||||||
| WormFlux | gene | WBGene00006948 | |||||||
| NDB | locus_tag | CELE_F52E4.6 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00006948|UniProtKB=Q20677 | |||||||
| family | PTHR46706 | ||||||||
| NCBI | gene | 180597 | |||||||
| RefSeq | protein | NM_076128.7 | |||||||
| TREEFAM | TREEFAM_ID | TF316084 | |||||||
| TrEMBL | UniProtAcc | Q20677 | |||||||
| UniProt_GCRP | UniProtAcc | Q20677 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:43 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | wrt | ||||||||
| Allele (28) | |||||||||
| Strain | WBStrain00007244 | ||||||||
| WBStrain00007245 | |||||||||
| WBStrain00007246 | |||||||||
| WBStrain00007914 | |||||||||
| WBStrain00032807 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| Ortholog (23) | |||||||||
| Paralog (24) | |||||||||
| Structured_description | Concise_description | wrt-2 encodes a hedgehog-like protein, with an N-terminal signalsequence, a Wart domain, and a C-terminal region of low-complexitysequence; WRT-2 is expressed in seam cells and hypodermal syncytia; theWart domain is predicted to form a cysteine-crosslinked protein involvedin intercellular signalling, and it has subtle similarity to theN-terminal Hedge domain of HEDGEHOG proteins; WRT-2 is weakly requiredfor normal molting; WRT-2 is also required for normal growth to fullsize and locomotion; all of these requirements may reflect commondefects in cholesterol-dependent hedgehog-like signalling or in vesicletrafficking; in two-hybrid assays, WRT-2 binds EYA-1, which may parallelthe derepression of Drosophila eyes absent by HEDGEHOG. | Paper_evidence | WBPaper00003717 | |||||
| WBPaper00006332 | |||||||||
| WBPaper00026841 | |||||||||
| WBPaper00027263 | |||||||||
| WBPaper00027697 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 05 Nov 2006 00:00:00 | ||||||||
| Automated_description | Expressed in hypodermal cell and hypodermis. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F52E4.6 | |||||||
| Corresponding_transcript | F52E4.6.1 | ||||||||
| Other_sequence (41) | |||||||||
| Associated_feature | WBsf653804 | ||||||||
| WBsf653805 | |||||||||
| WBsf1022564 | |||||||||
| WBsf1022565 | |||||||||
| WBsf1022566 | |||||||||
| WBsf237135 | |||||||||
| WBsf237136 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00077008 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00047999 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00076981 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00015424 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00032625 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr642 | ||||||||
| Expr13913 | |||||||||
| Expr1027232 | |||||||||
| Expr1032962 | |||||||||
| Expr1151814 | |||||||||
| Expr2018077 | |||||||||
| Expr2036215 | |||||||||
| Drives_construct (22) | |||||||||
| Construct_product | WBCnstr00034080 | ||||||||
| Microarray_results (18) | |||||||||
| Expression_cluster (251) | |||||||||
| Interaction (101) | |||||||||
| WBProcess | WBbiopr:00000123 | ||||||||
| Map_info | Map | X | Position | -12.232 | Error | 0.019344 | |||
| Positive | Positive_clone | F52E4 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00002823 | ||||||||
| WBPaper00003717 | |||||||||
| WBPaper00011801 | |||||||||
| WBPaper00024393 | |||||||||
| WBPaper00026841 | |||||||||
| WBPaper00027697 | |||||||||
| WBPaper00028754 | |||||||||
| WBPaper00031588 | |||||||||
| WBPaper00032049 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00055389 | |||||||||
| WBPaper00061387 | |||||||||
| WBPaper00064105 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
