WormBase Tree Display for Gene: WBGene00006789
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WBGene00006789 | SMap | S_parent | Sequence | CHROMOSOME_I | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 1 | |||||||
Name | CGC_name | unc-54 | Person_evidence | WBPerson261 | |||||
Sequence_name | F11C3.3 | ||||||||
Molecular_name | F11C3.3 | ||||||||
F11C3.3.1 | |||||||||
CE09349 | |||||||||
Other_name | myo-4 | ||||||||
CELE_F11C3.3 | Accession_evidence | NDB | BX284601 | ||||||
Public_name | unc-54 | ||||||||
DB_info | Database | AceView | gene | 1P454 | |||||
WormQTL | gene | WBGene00006789 | |||||||
WormFlux | gene | WBGene00006789 | |||||||
NDB | locus_tag | CELE_F11C3.3 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00006789|UniProtKB=P02566 | |||||||
family | PTHR45615 | ||||||||
NCBI | gene | 259839 | |||||||
RefSeq | protein | NM_061195.7 | |||||||
SwissProt | UniProtAcc | P02566 | |||||||
UniProt_GCRP | UniProtAcc | P02566 | |||||||
OMIM | gene | 160710 | |||||||
160720 | |||||||||
160740 | |||||||||
160741 | |||||||||
160760 | |||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:42 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | unc | ||||||||
Allele (386) | |||||||||
Legacy_information | Structural gene for major body wall myosin heavy chain. Reference null allele e190 : limp paralysed phenotype at all stages larvae can move slightly more than adults Egl; muscle ultrastructure very disorganized few thick filaments. ES3 ME0. NA (recessive) > 50 including e1108amber; e1301ts; e675sd and s291 (in frame internal deletion mutants with heavy chain fragment behavioral phenotype almost paralysed slight twitcher); also Tc1 insertion mutants; etc. Also unusual suppressor alleles (NA > 15) e.g. s74 : dominant suppressor of unc-22(s12) no other dominant phenotype recessive phenotype slow stiff normal muscle ultrastructure; alteration in S1 portion of protein. Also Class 3 (dominant) alleles reference allele e1152sd : severe rigid paralysis small; e1152/+ paralysed weaker phenotype. ES3 ME0. NA (dominant) > 10 : e1153 n489 etc.; resemble e1152 or more severe recessive lethal. Intragenic revertants have Class 1 phenotypes. | ||||||||
See unc-54. | |||||||||
See also e569, e576, e651, e675, e843, e903, e1008, e1009, e1021, e1092, e1108, e1115, e1152, e1153, e1157, e1168, e1201, e1213, e1219, e1223, e1257, e1258, e1273, e1274, e1300, e1301, e1311, e1315, e1328, e1360, e1419, e1420, n325, n326, n327, n489, n794, r274, r308, r322, r323, r327, r360, s74, s75, s76, s77, s78, s95, s291, s409, s411 | |||||||||
[C.elegansII] e190 : limp paralysed phenotype at all stages; larvae can move slightly more than adults; Egl; muscle ultrastructure very disorganized few thick filaments. ES3 ME0. OA>50 (recessive): e1108amb,e1301ts, e675sd and s291 (in frame internal deletion mutants, almost paralysed slight twitchers), etc. Also unusual suppressor alleles, OA>15: s74 (dominant suppressor of unc-22(s12), recessive slow, stiff; normal muscle ultrastructure) Also dominant antimorphic alleles, OA>10:e1152sd (severe rigid paralysis, small;e1152/+ paralysed weaker phenotype. ES3 ME0),r344 (recessive lethal, r344/+ severely paralysed), etc. Intragenic revertants have recessive paralysed phenotype. Some recessive alleles (r274, e1420 etc.) are dominant antimorphs in smg background. Cloned: encodes MHC B (MYO-4), major bodywall muscle myosin heavy chain. 6 kb message,1117 aa protein. Extensive molecular analysis. [Epstein et al. 1974; McLachlan and Karn 1982;Dibb et al. 1989; Bejsovec and Anderson 1990; TR; RW] | |||||||||
Strain (1380) | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (31) | |||||||||
Ortholog (82) | |||||||||
Paralog (21) | |||||||||
Structured_description (2) | |||||||||
Disease_info | Potential_model (30) | ||||||||
Molecular_info | Corresponding_CDS | F11C3.3 | |||||||
Corresponding_transcript | F11C3.3.1 | ||||||||
Other_sequence (386) | |||||||||
Associated_feature (32) | |||||||||
Experimental_info | RNAi_result (12) | ||||||||
Expr_pattern | Chronogram1695 | ||||||||
Expr571 | |||||||||
Expr732 | |||||||||
Expr735 | |||||||||
Expr747 | |||||||||
Expr1145 | |||||||||
Expr3837 | |||||||||
Expr5737 | |||||||||
Expr11395 | |||||||||
Expr16474 | |||||||||
Expr1025092 | |||||||||
Expr1032860 | |||||||||
Expr1148311 | |||||||||
Expr2017887 | |||||||||
Expr2036023 | |||||||||
Drives_construct (151) | |||||||||
Construct_product | WBCnstr00011688 | ||||||||
WBCnstr00011704 | |||||||||
WBCnstr00013869 | |||||||||
WBCnstr00015881 | |||||||||
WBCnstr00018819 | |||||||||
WBCnstr00034149 | |||||||||
Antibody (11) | |||||||||
Microarray_results (22) | |||||||||
Expression_cluster (308) | |||||||||
Interaction (231) | |||||||||
WBProcess | WBbiopr:00000040 | ||||||||
Map_info | Map | I | Position | 27.9607 | Error | 0.002243 | |||
Well_ordered | |||||||||
Positive | Inside_rearr | eDf3 | |||||||
eDf10 | |||||||||
dxDf2 | |||||||||
Positive_clone | F11C3 | Inferred_automatically | From sequence, transcript, pseudogene data | ||||||
SG25/36 | |||||||||
Mapping_data | 2_point (22) | ||||||||
Multi_point (47) | |||||||||
Pos_neg_data (20) | |||||||||
Landmark_gene | |||||||||
Reference (599) | |||||||||
Remark | unc-54 posneg pcr data gives map conflict, spans deletion breakpoint ? jah 8.97 | ||||||||
Method | Gene |