WormBase Tree Display for Gene: WBGene00006733
expand all nodes | collapse all nodes | view schema
WBGene00006733 | SMap | S_parent | Sequence | F19B6 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 1 | |||||||
Name | CGC_name | ufd-1 | Person_evidence | WBPerson50 | |||||
WBPerson2333 | |||||||||
Sequence_name | F19B6.2 | ||||||||
Molecular_name | F19B6.2a | ||||||||
F19B6.2a.1 | |||||||||
CE05667 | |||||||||
F19B6.2b | |||||||||
CE23674 | |||||||||
F19B6.2b.1 | |||||||||
Other_name | CELE_F19B6.2 | Accession_evidence | NDB | BX284604 | |||||
Public_name | ufd-1 | ||||||||
DB_info | Database (12) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:41 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | ufd | ||||||||
Allele (27) | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (22) | |||||||||
Contained_in_operon | CEOP4512 | ||||||||
Ortholog (40) | |||||||||
Structured_description (2) | |||||||||
Disease_info | Experimental_model | DOID:12583 | Homo sapiens | Paper_evidence | WBPaper00047004 | ||||
Curator_confirmed | WBPerson324 | ||||||||
Date_last_updated | 13 Sep 2017 00:00:00 | ||||||||
Potential_model | DOID:11198 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:12520) | |||||
DOID:5419 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:12520) | ||||||
Disease_relevance | 22q11.2 deletion syndrome (22q11.2DS) is the most common human deletion syndrome caused by deletion of a small piece of chromosome 22, characterized by neurodevelopmental defects, schizophrenia, congenital cardiac and craniofacial abnormalites (includes DiGeorge Syndrome and velocardiofacial syndrome); the 22q11.2 deletion overlaps several protein-coding genes including UFD1L (ubiquitin fusion degradation 1 like (yeast)); C. elegans ufd-1 is involved in ER-associated protein degradation and DNA replication and knock-down phenotypes include slow growth, defects in gonad development and locomotion, enlarged gut granules, cell cycle progression defects and reduced life span; ufd-1 provides a potential model system to study genes involved in 22q11.2DS. | Homo sapiens | Paper_evidence | WBPaper00047004 | |||||
WBPaper00032135 | |||||||||
Accession_evidence | OMIM | 611867 | |||||||
601754 | |||||||||
Curator_confirmed | WBPerson324 | ||||||||
Date_last_updated | 16 Sep 2015 00:00:00 | ||||||||
Models_disease_in_annotation | WBDOannot00000367 | ||||||||
Molecular_info | Corresponding_CDS | F19B6.2a | |||||||
F19B6.2b | |||||||||
Corresponding_transcript | F19B6.2a.1 | ||||||||
F19B6.2b.1 | |||||||||
Other_sequence (57) | |||||||||
Associated_feature | WBsf652288 | ||||||||
WBsf668415 | |||||||||
WBsf977009 | |||||||||
WBsf230999 | |||||||||
Experimental_info | RNAi_result (31) | ||||||||
Expr_pattern | Expr8954 | ||||||||
Expr1017281 | |||||||||
Expr1032808 | |||||||||
Expr1148964 | |||||||||
Expr2017747 | |||||||||
Expr2035886 | |||||||||
Drives_construct | WBCnstr00034187 | ||||||||
Construct_product | WBCnstr00006164 | ||||||||
WBCnstr00034187 | |||||||||
Antibody | WBAntibody00002589 | ||||||||
Microarray_results (30) | |||||||||
Expression_cluster (90) | |||||||||
Interaction (93) | |||||||||
WBProcess | WBbiopr:00000076 | ||||||||
Map_info | Map | IV | Position | 5.85046 | Error | 0.001284 | |||
Positive | Positive_clone | F19B6 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Pseudo_map_position | |||||||||
Reference (14) | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |