WormBase Tree Display for Gene: WBGene00006733
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| WBGene00006733 | SMap | S_parent | Sequence | F19B6 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | ufd-1 | Person_evidence | WBPerson50 | |||||
| WBPerson2333 | |||||||||
| Sequence_name | F19B6.2 | ||||||||
| Molecular_name | F19B6.2a | ||||||||
| F19B6.2a.1 | |||||||||
| CE05667 | |||||||||
| F19B6.2b | |||||||||
| CE23674 | |||||||||
| F19B6.2b.1 | |||||||||
| Other_name | CELE_F19B6.2 | Accession_evidence | NDB | BX284604 | |||||
| Public_name | ufd-1 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:41 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info (8) | |||||||||
| Disease_info | Experimental_model | DOID:12583 | Homo sapiens | Paper_evidence | WBPaper00047004 | ||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 13 Sep 2017 00:00:00 | ||||||||
| Potential_model | DOID:11198 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:12520) | |||||
| DOID:5419 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:12520) | ||||||
| Disease_relevance | 22q11.2 deletion syndrome (22q11.2DS) is the most common human deletion syndrome caused by deletion of a small piece of chromosome 22, characterized by neurodevelopmental defects, schizophrenia, congenital cardiac and craniofacial abnormalites (includes DiGeorge Syndrome and velocardiofacial syndrome); the 22q11.2 deletion overlaps several protein-coding genes including UFD1L (ubiquitin fusion degradation 1 like (yeast)); C. elegans ufd-1 is involved in ER-associated protein degradation and DNA replication and knock-down phenotypes include slow growth, defects in gonad development and locomotion, enlarged gut granules, cell cycle progression defects and reduced life span; ufd-1 provides a potential model system to study genes involved in 22q11.2DS. | Homo sapiens | Paper_evidence | WBPaper00047004 | |||||
| WBPaper00032135 | |||||||||
| Accession_evidence | OMIM | 611867 | |||||||
| 601754 | |||||||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 16 Sep 2015 00:00:00 | ||||||||
| Models_disease_in_annotation | WBDOannot00000367 | ||||||||
| Molecular_info | Corresponding_CDS | F19B6.2a | |||||||
| F19B6.2b | |||||||||
| Corresponding_transcript | F19B6.2a.1 | ||||||||
| F19B6.2b.1 | |||||||||
| Other_sequence (57) | |||||||||
| Associated_feature | WBsf652288 | ||||||||
| WBsf668415 | |||||||||
| WBsf977009 | |||||||||
| WBsf230999 | |||||||||
| Experimental_info | RNAi_result (31) | ||||||||
| Expr_pattern | Expr8954 | ||||||||
| Expr1017281 | |||||||||
| Expr1032808 | |||||||||
| Expr1148964 | |||||||||
| Expr2017747 | |||||||||
| Expr2035886 | |||||||||
| Drives_construct | WBCnstr00034187 | ||||||||
| Construct_product | WBCnstr00006164 | ||||||||
| WBCnstr00034187 | |||||||||
| Antibody | WBAntibody00002589 | ||||||||
| Microarray_results (30) | |||||||||
| Expression_cluster (90) | |||||||||
| Interaction (93) | |||||||||
| WBProcess | WBbiopr:00000076 | ||||||||
| Map_info | Map | IV | Position | 5.85046 | Error | 0.001284 | |||
| Positive | Positive_clone | F19B6 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (14) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
