WormBase Tree Display for Gene: WBGene00006673

WBGene00006673 SMap: S_parent: Sequence: C40C9
  Identity: Version: 1
    Name: CGC_name: twk-20 Person_evidence: WBPerson655
      Sequence_name: C40C9.1
      Molecular_name: C40C9.1
        C40C9.1.1
        CE24839
      Other_name: CELE_C40C9.1 Accession_evidence: NDB BX284606
      Public_name: twk-20
    DB_info: Database: AceView gene XO261
        WormQTL gene WBGene00006673
        WormFlux gene WBGene00006673
        NDB locus_tag CELE_C40C9.1
        Panther gene CAEEL|WormBase=WBGene00006673|UniProtKB=G5ECW6
          family PTHR11003
        NCBI gene 181485
        RefSeq protein NM_077883.2
        TrEMBL UniProtAcc G5ECW6
        UniProt_GCRP UniProtAcc G5ECW6
        OMIM gene 603220
            605874
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:41 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: twk
    Allele (50)
    Legacy_information: [Thomas JH] twk for potassium channel family, type Twik (double P domain). Predicted gene ZK1067.5
      [Thomas JH] twk for potassium channel family, type Twik (double P domain). Predicted gene C40C9.1
    Strain: WBStrain00026426
    RNASeq_FPKM (74)
    GO_annotation (15)
    Ortholog (32)
    Paralog (47)
    Structured_description: Automated_description: Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be located in membrane. Expressed in muscle cell and neurons. Human ortholog(s) of this gene implicated in Birk-Barel syndrome and primary pulmonary hypertension. Is an ortholog of human KCNK3 (potassium two pore domain channel subfamily K member 3) and KCNK9 (potassium two pore domain channel subfamily K member 9). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:14557 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:6278)
      DOID:0050675 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:6283)
  Molecular_info: Corresponding_CDS: C40C9.1
    Corresponding_transcript: C40C9.1.1
    Other_sequence: SS02538
      JI246191.1
      SSC05256_1
    Associated_feature: WBsf717391
      WBsf1007674
      WBsf1007675
      WBsf1024267
      WBsf1024268
      WBsf236596
  Experimental_info: RNAi_result: WBRNAi00027783 Inferred_automatically: RNAi_primary
      WBRNAi00042248 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1370
      Expr1012496
      Expr1146239
      Expr2017647
      Expr2035787
    Drives_construct: WBCnstr00010244
      WBCnstr00034224
    Construct_product: WBCnstr00010244
      WBCnstr00034224
    Microarray_results (18)
    Expression_cluster (29)
    Interaction (11)
  Map_info: Map: X Position: 14.0098 Error: 0.006152
    Positive: Positive_clone: C40C9 Person_evidence: WBPerson654
            WBPerson655
          Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00026748
    WBPaper00038487
    WBPaper00038491
    WBPaper00055090
  Remark: twk-20 was connected to ZK1067.5 CGC_data_submission
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene