WormBase Tree Display for Gene: WBGene00006536
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| WBGene00006536 | SMap | S_parent | Sequence | K01G5 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | tbb-1 | |||||||
| Sequence_name | K01G5.7 | ||||||||
| Molecular_name | K01G5.7 | ||||||||
| K01G5.7.1 | |||||||||
| CE16197 | |||||||||
| Other_name | TUBB7 | ||||||||
| CELE_K01G5.7 | Accession_evidence | NDB | BX284603 | ||||||
| Public_name | tbb-1 | ||||||||
| DB_info | Database | AceView | gene | 3L832 | |||||
| WormQTL | gene | WBGene00006536 | |||||||
| WormFlux | gene | WBGene00006536 | |||||||
| NDB | locus_tag | CELE_K01G5.7 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00006536|UniProtKB=O17921 | |||||||
| family | PTHR11588 | ||||||||
| NCBI | gene | 176501 | |||||||
| RefSeq | protein | NM_066966.9 | |||||||
| TrEMBL | UniProtAcc | O17921 | |||||||
| UniProt_GCRP | UniProtAcc | O17921 | |||||||
| OMIM | gene | 191130 | |||||||
| 602662 | |||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:40 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | tbb | ||||||||
| Allele (31) | |||||||||
| Legacy_information | [C.elegansII] NMK. Encodes beta tubulin. [NW] | ||||||||
| Strain | WBStrain00035711 | ||||||||
| WBStrain00007876 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (17) | |||||||||
| Contained_in_operon | CEOP3700 | ||||||||
| Ortholog (57) | |||||||||
| Paralog (16) | |||||||||
| Structured_description | Concise_description | This gene encodes a homolog of mammalian beta-tubulin (TUBB) that is expressed at high levels in the germline; TBB-1 is redundant for embryonic viability, due to its paralog TBB-2. | Paper_evidence | WBPaper00004588 | |||||
| WBPaper00006305 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Located in spindle microtubule. Expressed in several structures, including excretory gland cell; intestine; nervous system; pharynx; and uv1. Human ortholog(s) of this gene implicated in brain disease (multiple) and congenital symmetric circumferential skin creases 1. Is an ortholog of human TUBB (tubulin beta class I) and TUBB4A (tubulin beta 4A class IVa). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0112242 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:20778) | ||||
| DOID:0090136 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:20778) | ||||||
| DOID:0060798 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:20774) | ||||||
| DOID:0090041 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:20774) | ||||||
| Molecular_info | Corresponding_CDS | K01G5.7 | |||||||
| Corresponding_transcript | K01G5.7.1 | ||||||||
| Other_sequence (214) | |||||||||
| Associated_feature | WBsf651476 | ||||||||
| WBsf651477 | |||||||||
| WBsf667407 | |||||||||
| WBsf667408 | |||||||||
| WBsf667409 | |||||||||
| WBsf981572 | |||||||||
| WBsf1015846 | |||||||||
| WBsf227498 | |||||||||
| WBsf227499 | |||||||||
| Experimental_info | RNAi_result (34) | ||||||||
| Expr_pattern | Expr13371 | ||||||||
| Expr15253 | |||||||||
| Expr1012241 | |||||||||
| Expr1032685 | |||||||||
| Expr1153365 | |||||||||
| Expr2017317 | |||||||||
| Expr2035452 | |||||||||
| Drives_construct | WBCnstr00008030 | ||||||||
| WBCnstr00018946 | |||||||||
| WBCnstr00020183 | |||||||||
| WBCnstr00034317 | |||||||||
| Construct_product | WBCnstr00001986 | ||||||||
| WBCnstr00018946 | |||||||||
| WBCnstr00021845 | |||||||||
| WBCnstr00034317 | |||||||||
| WBCnstr00038428 | |||||||||
| Antibody | WBAntibody00000711 | ||||||||
| WBAntibody00001670 | |||||||||
| Microarray_results (18) | |||||||||
| Expression_cluster (170) | |||||||||
| Interaction (195) | |||||||||
| Map_info | Map | III | Position | 5.08225 | Error | 0.011334 | |||
| Positive | Positive_clone | K01G5 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| NW#B7 | |||||||||
| Mapping_data | Multi_point | 4722 | |||||||
| Pseudo_map_position | |||||||||
| Reference (28) | |||||||||
| Remark | Sequence connection from [Lu C, Mains PE, Culotti JG] | ||||||||
| The seqence connection of tbb-1 to ZK154.3 and mec-7 as an other-name of tbb-1 mentioned in cgc3909 is not approved by CGC. | CGC_data_submission | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
