WormBase Tree Display for Gene: WBGene00006510
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| WBGene00006510 | SMap | S_parent | Sequence | C01G6 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | mtrr-1 | Person_evidence | WBPerson1711 | |||||
| Sequence_name | C01G6.6 | ||||||||
| Molecular_name | C01G6.6a | ||||||||
| C01G6.6a.1 | |||||||||
| CE00868 | |||||||||
| C01G6.6b | |||||||||
| Other_name | tag-165 | ||||||||
| CELE_C01G6.6 | Accession_evidence | NDB | BX284602 | ||||||
| Public_name | mtrr-1 | ||||||||
| DB_info | Database (14) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:40 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 20 Apr 2011 10:05:24 | WBPerson2970 | Name_change | CGC_name | mtrr-1 | ||||
| Other_name | tag-165 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | mtrr | ||||||||
| Allele (49) | |||||||||
| Strain | WBStrain00035852 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (13) | |||||||||
| Ortholog (38) | |||||||||
| Paralog | WBGene00001262 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00001485 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00021314 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | C01G6.6 encodes an ortholog of the human gene METHIONINE SYNTHASE REDUCTASE (MTRR), which when mutated leads to homocystinuria (OMIM:236270) | Paper_evidence | WBPaper00004637 | |||||
| Curator_confirmed | WBPerson1823 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 09 Aug 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable FMN binding activity; [methionine synthase] reductase activity; and flavin adenine dinucleotide binding activity. Predicted to be involved in homocysteine metabolic process and methionine biosynthetic process. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in several diseases, including endocrine gland cancer (multiple); hematologic cancer (multiple); and homocystinuria. Is an ortholog of human MTRR (5-methyltetrahydrofolate-homocysteine methyltransferase reductase). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model (17) | ||||||||
| Molecular_info | Corresponding_CDS | C01G6.6a | |||||||
| Corresponding_CDS_history | C01G6.6b:wp252 | ||||||||
| Corresponding_transcript | C01G6.6b | ||||||||
| C01G6.6a.1 | |||||||||
| Other_sequence (33) | |||||||||
| Associated_feature (11) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00039357 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00028306 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00009953 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00062102 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00107057 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00107059 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1020855 | ||||||||
| Expr1032666 | |||||||||
| Expr1143473 | |||||||||
| Expr2013817 | |||||||||
| Expr2032057 | |||||||||
| Drives_construct | WBCnstr00037892 | ||||||||
| Construct_product | WBCnstr00037892 | ||||||||
| Microarray_results (35) | |||||||||
| Expression_cluster (166) | |||||||||
| Interaction (46) | |||||||||
| Map_info | Map | II | Position | 1.0987 | Error | 0.000654 | |||
| Positive | Positive_clone | C01G6 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00028527 | ||||||||
| WBPaper00038491 | |||||||||
| WBPaper00049828 | |||||||||
| WBPaper00049923 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00060431 | |||||||||
| WBPaper00064989 | |||||||||
| WBPaper00065026 | |||||||||
| WBPaper00066161 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
