Predicted to enable peptidase activity and serine-type endopeptidase inhibitor activity. Involved in IRE1-mediated unfolded protein response. Predicted to be located in extracellular space. Human ortholog(s) of this gene implicated in several diseases, including IgA glomerulonephritis; autosomal recessive nonsyndromic deafness 91; and thrombophilia (multiple). Is an ortholog of several human genes including SERPINB1 (serpin family B member 1); SERPINB8 (serpin family B member 8); and SERPINC1 (serpin family C member 1).
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.