WormBase Tree Display for Gene: WBGene00005158
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| WBGene00005158 | Identity | Version | 1 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Name | CGC_name | srf-9 | Person_evidence | WBPerson494 | |||||
| Public_name | srf-9 | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:37 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Gene_class | srf | |||||||
| Allele | WBVar00142844 | Inferred_automatically | From strain object: CL208 | ||||||
| WBVar00142853 | |||||||||
| Legacy_information | [C.elegansII] dv4 : altered cuticle labelling, ectopic WGA lectin binding, pleiotropic defects: Unc, Egl, Mab, Mig(DTC), variable neuronal abnormalities, SDS-sensitive dauers; enhance lin-12(gf),OA1: dv16. [Link et al. 1992; CL] | ||||||||
| Strain | WBStrain00005057 | ||||||||
| Structured_description | Concise_description | srf-9 was identified as a mutation that alters the surface antigenicity of the cuticle in C. elegans; srf-9 mutations show altered binding to antibodies raised against the cuticles of wild-type worms, and lectins like wheat germ agglutinin; srf-9 mutants also show uncoordinated movement, abnormal gonadal and male tail morphologies, and male infertility. | Paper_evidence | WBPaper00001576 | |||||
| WBPaper00001706 | |||||||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 10 Oct 2011 00:00:00 | ||||||||
| Disease_info | Disease_relevance | C. elegans is used as a model system to study bacterial adherence via biofilm formation and to identify genes in the infectious agent as well as the host that are required for infection; elegans srf genes are required for cuticle surface properties like binding to antigens, and for the adherence of bacterial pathogens like Yersinia pseduotuberculosis and Yersinia pestis via biofilms. | Homo sapiens | Paper_evidence | WBPaper00001706 | ||||
| WBPaper00026735 | |||||||||
| WBPaper00029153 | |||||||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 06 Mar 2013 00:00:00 | ||||||||
| Experimental_info | Interaction | WBInteraction000052127 | |||||||
| Map_info | Map | V | Position | 1.34323 | Error | 0.024558 | |||
| Mapping_data | 2_point | 5514 | |||||||
| Multi_point | 1861 | ||||||||
| 1862 | |||||||||
| Pos_neg_data | 5511 | ||||||||
| 5512 | |||||||||
| 5513 | |||||||||
| Reference (13) | |||||||||
| Method | Gene |
