WormBase Tree Display for Gene: WBGene00004979

WBGene00004979 SMap: S_parent: Sequence: F42G8
  Identity: Version: 1
    Name: CGC_name: sph-1 Person_evidence: WBPerson451
      Sequence_name: F42G8.11
      Molecular_name: F42G8.11
        F42G8.11.1
        CE40059
      Other_name: CELE_F42G8.11 Accession_evidence: NDB BX284604
      Public_name: sph-1
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:37 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: sph
    Allele (23)
    Strain: WBStrain00031923
      WBStrain00036200
      WBStrain00003813
    RNASeq_FPKM (74)
    GO_annotation: 00032640
      00032641
      00032642
      00032643
      00032644
      00113388
      00113389
    Ortholog: WBGene00059423 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00075027 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00024773 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00141583 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00123654 Caenorhabditis japonica From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      CBOVI.g8036 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g194 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g15900 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g7075 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g7204 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g17116 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g12796 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g8599 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g27268 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g12903 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cni-sph-1 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold629.g8482 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00273.g8457 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_15955 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_014753 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g07733 Oscheius tipulae From_analysis: WormBase-Compara
      Sp34_40109500 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrIV_pilon.g10998 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00293199 Trichuris muris From_analysis: WormBase-Compara
      ZFIN:ZDB-GENE-030616-625 Danio rerio From_analysis: Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-040426-1434 Danio rerio From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      ZFIN:ZDB-GENE-040718-205 Danio rerio From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      ZFIN:ZDB-GENE-141212-294 Danio rerio From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-031104-2 Danio rerio From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      ZFIN:ZDB-GENE-050417-309 Danio rerio From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      ZFIN:ZDB-GENE-110420-2 Danio rerio From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:11506 Homo sapiens From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
      HGNC:11507 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
      HGNC:16507 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
      HGNC:27638 Homo sapiens From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
      MGI:1328311 Mus musculus From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
      MGI:108081 Mus musculus From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
      MGI:98467 Mus musculus From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
      MGI:1919253 Mus musculus From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
      RGD:3802 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
      RGD:708366 Rattus norvegicus From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
      RGD:1309907 Rattus norvegicus From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
      RGD:1359569 Rattus norvegicus From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
    Structured_description: Concise_description: sph-1 encodes a member of the synaptophysin/synaptoporin family that contains a MARVEL domain, a membrane-associating domain found in lipid-associating proteins, and contains a transmembrane domain. Curator_confirmed: WBPerson48
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Located in cytoplasmic vesicle. Expressed in anal sphincter muscle and pharyngeal muscle cell. Human ortholog(s) of this gene implicated in Alzheimer's disease and non-syndromic X-linked intellectual disability 96. Is an ortholog of human SYNPR (synaptoporin) and SYPL1 (synaptophysin like 1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:10652 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:11506)
      DOID:0112035 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:11506)
  Molecular_info: Corresponding_CDS: F42G8.11
    Corresponding_CDS_history: F42G8.11:wp156
    Corresponding_transcript: F42G8.11.1
    Other_sequence (24)
    Associated_feature: WBsf651983
      WBsf651984
      WBsf668084
      WBsf230386
  Experimental_info: RNAi_result: WBRNAi00047123 Inferred_automatically: RNAi_primary
      WBRNAi00014841 Inferred_automatically: RNAi_primary
      WBRNAi00032152 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr3982
      Expr1020981
      Expr1032477
      Expr1150991
      Expr2016054
      Expr2034289
    Drives_construct: WBCnstr00011795
      WBCnstr00035295
    Construct_product: WBCnstr00035295
    Microarray_results (18)
    Expression_cluster (114)
    Interaction: WBInteraction000120132
      WBInteraction000122897
      WBInteraction000122898
      WBInteraction000134602
      WBInteraction000166894
      WBInteraction000180665
      WBInteraction000193904
      WBInteraction000428878
      WBInteraction000444399
  Map_info: Map: IV Position: 3.61293 Error: 0.001689
    Positive: Positive_clone: F42G8 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4986
        4448
        5613
    Pseudo_map_position
  Reference: WBPaper00027627
    WBPaper00028886
    WBPaper00031849
    WBPaper00038491
    WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene