WormBase Tree Display for Gene: WBGene00004298
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| WBGene00004298 | Evidence | CGC_data_submission | |||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | CHROMOSOME_I | ||||||
| Identity | Version | 2 | |||||||
| Name | CGC_name | rad-54.L | Person_evidence | WBPerson195 | |||||
| WBPerson1720 | |||||||||
| Sequence_name | W06D4.6 | ||||||||
| Molecular_name | W06D4.6 | ||||||||
| W06D4.6.1 | |||||||||
| CE25143 | |||||||||
| Other_name | rad-54 | ||||||||
| CELE_W06D4.6 | Accession_evidence | NDB | BX284601 | ||||||
| Public_name | rad-54.L | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:34 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 04 Jul 2019 12:06:02 | WBPerson1983 | Name_change | CGC_name | rad-54.L | ||||
| Other_name | rad-54 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | rad | ||||||||
| Allele (58) | |||||||||
| Strain | WBStrain00035848 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00016692 | ||||||||
| 00016693 | |||||||||
| 00016694 | |||||||||
| 00016695 | |||||||||
| 00016696 | |||||||||
| 00016697 | |||||||||
| 00016698 | |||||||||
| 00112631 | |||||||||
| 00112632 | |||||||||
| Ortholog (38) | |||||||||
| Paralog (19) | |||||||||
| Structured_description | Concise_description | rad-54 encodes a protein that belongs to the DEAD-like helicase superfamily, and shares similarity with Saccharomyces cerevisiae Rad54, and human RAD54L, proteins known to be involved in the homologous recombination (HR) and repair of DNA; in elegans, rad-54 acts in a HR pathway, downstream of a nucleotide excision repair (NER) pathway, to promote ultraviolet induced apoptosis of damaged cells. | Paper_evidence | WBPaper00037879 | |||||
| WBPaper00035885 | |||||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson1823 | |||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 09 Sep 2013 00:00:00 | ||||||||
| Automated_description | Enables ATP-dependent activity, acting on DNA. Predicted to be involved in double-strand break repair via synthesis-dependent strand annealing and reciprocal meiotic recombination. Located in nucleus. Human ortholog(s) of this gene implicated in breast cancer; non-Hodgkin lymphoma; and pancreatic cancer. Is an ortholog of human RAD54L (RAD54 like). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0060060 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9826) | ||||
| DOID:14566 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9826) | ||||||
| DOID:1793 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9826) | ||||||
| DOID:1612 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9826) | ||||||
| Molecular_info | Corresponding_CDS | W06D4.6 | |||||||
| Corresponding_transcript | W06D4.6.1 | ||||||||
| Other_sequence (33) | |||||||||
| Associated_feature | WBsf218248 | ||||||||
| Experimental_info | RNAi_result (21) | ||||||||
| Expr_pattern | Expr1013806 | ||||||||
| Expr1032124 | |||||||||
| Expr1158433 | |||||||||
| Expr2015242 | |||||||||
| Expr2033476 | |||||||||
| Drives_construct | WBCnstr00007713 | ||||||||
| WBCnstr00035582 | |||||||||
| Construct_product | WBCnstr00007713 | ||||||||
| WBCnstr00035582 | |||||||||
| Microarray_results (20) | |||||||||
| Expression_cluster (134) | |||||||||
| Interaction (103) | |||||||||
| Map_info | Map | I | Position | 3.48577 | Error | 0.010523 | |||
| Positive | Positive_clone | W06D4 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (22) | |||||||||
| Remark | Sequence connection from [Boulton S, Vidal M] | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
