WormBase Tree Display for Gene: WBGene00004193

WBGene00004193 Evidence: Paper_evidence: WBPaper00005877
  SMap: S_parent: Sequence: C15H9
  Identity: Version: 2
    Name: CGC_name: prx-3
      Sequence_name: C15H9.8
      Molecular_name: C15H9.8a
        C15H9.8a.1
        CE41868
        C15H9.8b
        CE06836
        C15H9.8b.1
      Other_name: CELE_C15H9.8 Accession_evidence: NDB BX284606
      Public_name: prx-3
    DB_info: Database: WormQTL gene WBGene00004193
        WormFlux gene WBGene00004193
        NDB locus_tag CELE_C15H9.8
        Panther gene CAEEL|WormBase=WBGene00004193|UniProtKB=Q18028
          family PTHR28080
        NCBI gene 182644
        RefSeq protein NM_001392784.1
            NM_001129639.3
        TREEFAM TREEFAM_ID TF352826
        TrEMBL UniProtAcc Q18028
            Q18027
        UniProt_GCRP UniProtAcc Q18028
        OMIM gene 603164
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:34 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 30 Nov 2007 08:46:02 WBPerson1867 Event: Acquires_merge: WBGene00015804
      Acquires_merge: WBGene00015804
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: prx
    Allele (32)
    RNASeq_FPKM (74)
    GO_annotation: 00059997
      00059998
      00059999
      00060000
      00112464
      00112465
    Ortholog: WBGene00051567 Caenorhabditis remanei From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00164571 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00133951 Caenorhabditis japonica From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00035225 Caenorhabditis briggsae From_analysis: Inparanoid_8
            WormBase-Compara
      WBGene00107017 Pristionchus pacificus From_analysis: Inparanoid_8
            WormBase-Compara
      WBGene00222488 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g3324 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g5681 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g21977 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g10647 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g2615 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g16085 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g219 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g5787 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g7245 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g13970 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00157.g5826 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cni-prx-3 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold626.g6522 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00209.g7102 Caenorhabditis sinica From_analysis: WormBase-Compara
      Csp5_scaffold_01110.g18459 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_00412 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_024521 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g14584 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g12502 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_X0229910 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrX_pilon.g19173 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00239182 Onchocerca volvulus From_analysis: WormBase-Compara
      SGD:S000002737 Saccharomyces cerevisiae From_analysis: OrthoFinder
            Panther
      FB:FBgn0036484 Drosophila melanogaster From_analysis: OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
      ZFIN:ZDB-GENE-040426-979 Danio rerio From_analysis: Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:8858 Homo sapiens From_analysis: Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:1929646 Mus musculus From_analysis: Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
      RGD:621636 Rattus norvegicus From_analysis: Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
    Structured_description: Concise_description: prx-3 is orthologous to the human gene PEROXISOMAL BIOGENESIS FACTOR 3 (PEX3; OMIM:603164), which when mutated leads to Zellweger syndrome of complementation group G. Curator_confirmed: WBPerson1823
            WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable protein-macromolecule adaptor activity. Predicted to be involved in protein import into peroxisome membrane. Predicted to be located in peroxisomal membrane. Human ortholog(s) of this gene implicated in peroxisome biogenesis disorder 10A. Is an ortholog of human PEX3 (peroxisomal biogenesis factor 3). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0080484 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:8858)
      DOID:0080377 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:8858)
  Molecular_info: Corresponding_CDS: C15H9.8a
      C15H9.8b
    Corresponding_CDS_history: C15H9.8:wp185
    Corresponding_transcript: C15H9.8a.1
      C15H9.8b.1
    Other_sequence: CJC03027_1
      CRC00430_1
      CR08385
      Tcir_isotig25493
      CBC11882_1
    Associated_feature: WBsf654045
      WBsf237441
      WBsf237442
  Experimental_info: RNAi_result (11)
    Expr_pattern: Expr1017263
      Expr1032053
      Expr1144693
      Expr2015126
      Expr2033364
    Construct_product: WBCnstr00022628
    Microarray_results (37)
    Expression_cluster (147)
    Interaction: WBInteraction000036526
      WBInteraction000181958
      WBInteraction000280074
      WBInteraction000325933
      WBInteraction000346563
      WBInteraction000383669
      WBInteraction000575899
      WBInteraction000585711
      WBInteraction000586669
  Map_info: Map: X Position: -3.70322
    Positive: Positive_clone: C15H9 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00005877
    WBPaper00006517
    WBPaper00038491
    WBPaper00055090
    WBPaper00056693
    WBPaper00059323
    WBPaper00064552
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene