WormBase Tree Display for Gene: WBGene00003891
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| WBGene00003891 | SMap | S_parent | Sequence | F11C7 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | osm-11 | Person_evidence | WBPerson242 | |||||
| Sequence_name | F11C7.5 | ||||||||
| Molecular_name | F11C7.5 | ||||||||
| F11C7.5.1 | |||||||||
| CE17657 | |||||||||
| F11C7.5.2 | |||||||||
| Other_name | sel-14 | Paper_evidence | WBPaper00032102 | ||||||
| CELE_F11C7.5 | Accession_evidence | NDB | BX284606 | ||||||
| Public_name | osm-11 | ||||||||
| DB_info | Database | AceView | gene | XS34 | |||||
| WormQTL | gene | WBGene00003891 | |||||||
| WormFlux | gene | WBGene00003891 | |||||||
| NDB | locus_tag | CELE_F11C7.5 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00003891|UniProtKB=O45346 | |||||||
| family | PTHR35015 | ||||||||
| NCBI | gene | 181772 | |||||||
| RefSeq | protein | NM_078422.9 | |||||||
| SwissProt | UniProtAcc | O45346 | |||||||
| TREEFAM | TREEFAM_ID | TF315672 | |||||||
| UniProt_GCRP | UniProtAcc | O45346 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:33 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 06 Jul 2007 16:22:11 | WBPerson2970 | Event | Acquires_merge | WBGene00017377 | ||||
| Acquires_merge | WBGene00017377 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | osm | ||||||||
| Allele (38) | |||||||||
| Legacy_information | [C.elegansII] n1604 : defective osmotic avoidance. NA1. [MT; JT] | ||||||||
| Strain | WBStrain00027083 | ||||||||
| WBStrain00027087 | |||||||||
| WBStrain00008296 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (16) | |||||||||
| Ortholog (27) | |||||||||
| Paralog | WBGene00003887 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WBGene00019640 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| WBGene00019331 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WBGene00013980 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| Structured_description | Concise_description | osm-11 encodes a protein required for normal osmosensation, osmotic resistance, and defecation rhythm, and for fully normal growth rate; OSM-11 has no clear orthologs outside of nematodes, but is paralogous to DOS-1, OSM-7, and K02F3.7, has a predicted signal sequence with 12 conserved cysteine residues, and may be secreted; osm-11 mutants have abnormally high levels of internal glycerol, defective osmotic avoidance, and slowed defecation rhythms characteristic of worms under chronic osmotic stress; osm-11 mutants are also somewhat scrawny and slow-growing; osm-11(RNAi) animals show constitutive gpdh-1 transcription. | Paper_evidence | WBPaper00028383 | |||||
| WBPaper00028499 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 29 Mar 2008 00:00:00 | ||||||||
| Automated_description | Enables Notch binding activity. Involved in several processes, including positive regulation of Notch signaling pathway; response to osmotic stress; and vulval development. Located in apical part of cell and extracellular space. Expressed in several structures, including P3.p hermaphrodite; P4.p hermaphrodite; P5.p hermaphrodite; P8.p hermaphrodite; and hermaphrodite gonad. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F11C7.5 | |||||||
| Corresponding_transcript | F11C7.5.1 | ||||||||
| F11C7.5.2 | |||||||||
| Other_sequence (32) | |||||||||
| Associated_feature (12) | |||||||||
| Experimental_info | RNAi_result (23) | ||||||||
| Expr_pattern | Expr8248 | ||||||||
| Expr8249 | |||||||||
| Expr9280 | |||||||||
| Expr1016420 | |||||||||
| Expr1031834 | |||||||||
| Expr1148316 | |||||||||
| Expr2014640 | |||||||||
| Expr2032873 | |||||||||
| Drives_construct | WBCnstr00013209 | ||||||||
| WBCnstr00035809 | |||||||||
| Construct_product | WBCnstr00008293 | ||||||||
| WBCnstr00008611 | |||||||||
| WBCnstr00008612 | |||||||||
| WBCnstr00008613 | |||||||||
| WBCnstr00008614 | |||||||||
| WBCnstr00008615 | |||||||||
| WBCnstr00008618 | |||||||||
| WBCnstr00035809 | |||||||||
| Regulate_expr_cluster | WBPaper00035873:osm-11_regulated | ||||||||
| Antibody | WBAntibody00001447 | ||||||||
| Microarray_results (21) | |||||||||
| Expression_cluster (198) | |||||||||
| Interaction (44) | |||||||||
| Map_info | Map | X | Position | 24.0914 | Error | 0.001543 | |||
| Positive | Positive_clone | F11C7 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | 2_point | 3731 | |||||||
| Multi_point | 1369 | ||||||||
| Pos_neg_data | 3732 | ||||||||
| 3733 | |||||||||
| 3734 | |||||||||
| 3735 | |||||||||
| 3736 | |||||||||
| Reference (32) | |||||||||
| Method | Gene |
