WormBase Tree Display for Gene: WBGene00003515
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WBGene00003515 | SMap | S_parent | Sequence | K12F2 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 1 | |||||||
Name | CGC_name | myo-3 | Person_evidence | WBPerson261 | |||||
Sequence_name | K12F2.1 | ||||||||
Molecular_name | K12F2.1 | ||||||||
K12F2.1.1 | |||||||||
CE34936 | |||||||||
Other_name | sup-3 | ||||||||
CELE_K12F2.1 | Accession_evidence | NDB | BX284605 | ||||||
Public_name | myo-3 | ||||||||
DB_info | Database | AceView | gene | 5M708 | |||||
WormQTL | gene | WBGene00003515 | |||||||
WormFlux | gene | WBGene00003515 | |||||||
NDB | locus_tag | CELE_K12F2.1 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00003515|UniProtKB=P12844 | |||||||
family | PTHR45615 | ||||||||
NCBI | gene | 179676 | |||||||
RefSeq | protein | NM_073664.7 | |||||||
SwissProt | UniProtAcc | P12844 | |||||||
UniProt_GCRP | UniProtAcc | P12844 | |||||||
OMIM | gene | 160710 | |||||||
160720 | |||||||||
160740 | |||||||||
160741 | |||||||||
160760 | |||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:32 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | myo | ||||||||
Allele (121) | |||||||||
Legacy_information (5) | |||||||||
Strain (34) | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (31) | |||||||||
Ortholog (80) | |||||||||
Paralog (21) | |||||||||
Structured_description | Concise_description | myo-3 encodes MHC A, the minor isoform of MHC (myosin heavy chain) that is essential for thick filament formation, and for viability, movement, and embryonic elongation; expressed in body muscle, the somatic sheath cell covering the hermaphrodite gonad, and also expressed in enteric muscle, vulval muscles of the hermaphrodite and the diagonal muscles of the male tail. | Paper_evidence (11) | ||||||
Curator_confirmed | WBPerson48 | ||||||||
Date_last_updated | 21 Jan 2005 00:00:00 | ||||||||
Automated_description | Enables cytoskeletal motor activity. Involved in locomotory behavior and positive regulation of ovulation. Located in A band and striated muscle myosin thick filament. Expressed in body wall musculature; enteric muscle; gonad; vulval muscle; and in male. Human ortholog(s) of this gene implicated in several diseases, including congenital heart disease (multiple); distal myopathy 1; and intrinsic cardiomyopathy (multiple). Is an ortholog of several human genes including MYH1 (myosin heavy chain 1); MYH2 (myosin heavy chain 2); and MYH3 (myosin heavy chain 3). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model (30) | ||||||||
Molecular_info | Corresponding_CDS | K12F2.1 | |||||||
Corresponding_CDS_history | K12F2.1:wp106 | ||||||||
Corresponding_transcript | K12F2.1.1 | ||||||||
Other_sequence (194) | |||||||||
Associated_feature (11) | |||||||||
Experimental_info | RNAi_result (11) | ||||||||
Expr_pattern (14) | |||||||||
Drives_construct (391) | |||||||||
Construct_product | WBCnstr00009392 | ||||||||
WBCnstr00019120 | |||||||||
WBCnstr00021706 | |||||||||
WBCnstr00036079 | |||||||||
Antibody | WBAntibody00000014 | ||||||||
WBAntibody00000019 | |||||||||
WBAntibody00000391 | |||||||||
WBAntibody00001784 | |||||||||
Microarray_results (18) | |||||||||
Expression_cluster (285) | |||||||||
Interaction (183) | |||||||||
WBProcess | WBbiopr:00000006 | ||||||||
WBbiopr:00000040 | |||||||||
Map_info | Map | V | Position | 3.84005 | Error | 0.021073 | |||
Well_ordered | |||||||||
Positive | Positive_clone | K12F2 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
SG25/35 | |||||||||
Mapping_data | 2_point | 141 | |||||||
315 | |||||||||
3133 | |||||||||
3134 | |||||||||
Multi_point | 148 | ||||||||
782 | |||||||||
1176 | |||||||||
1177 | |||||||||
1178 | |||||||||
2809 | |||||||||
2817 | |||||||||
5284 | |||||||||
Pos_neg_data | 300 | ||||||||
3135 | |||||||||
854 | |||||||||
866 | |||||||||
Reference (284) | |||||||||
Remark | Data extracted from Williams & Waterston 1994 | ||||||||
yk1d8.5,yk1d8.3, removed from sequence list sdm 11/00 | |||||||||
Method | Gene |