WormBase Tree Display for Gene: WBGene00003468
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| WBGene00003468 | SMap | S_parent | Sequence | ZK354 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | msp-113 | Person_evidence | WBPerson680 | |||||
| Sequence_name | ZK354.4 | ||||||||
| Molecular_name | ZK354.4 | ||||||||
| ZK354.4.1 | |||||||||
| CE02806 | |||||||||
| Other_name | CELE_ZK354.4 | Accession_evidence | NDB | BX284604 | |||||
| Public_name | msp-113 | ||||||||
| DB_info | Database | AceView | gene | 4G63 | |||||
| WormQTL | gene | WBGene00003468 | |||||||
| WormFlux | gene | WBGene00003468 | |||||||
| NDB | locus_tag | CELE_ZK354.4 | |||||||
| NCBI | gene | 259801 | |||||||
| RefSeq | protein | NM_068372.8 | |||||||
| SwissProt | UniProtAcc | P53017 | |||||||
| UniProt_GCRP | UniProtAcc | P53017 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:32 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | msp | ||||||||
| Allele | WBVar01499365 | ||||||||
| WBVar01499395 | |||||||||
| WBVar01499396 | |||||||||
| WBVar00909654 | |||||||||
| WBVar01499242 | |||||||||
| WBVar01499633 | |||||||||
| WBVar01500245 | |||||||||
| WBVar02133880 | |||||||||
| Legacy_information | Cluster of six genes including msp-19 and msp-113 (both transcribed). | ||||||||
| [C.elegansII] NMK. Encodes MSP (16kD). Defines cluster of at least six genes including msp-19 and msp-113 (both transcribed). [Ward et al. (1988); BA] | |||||||||
| RNASeq_FPKM (74) | |||||||||
| Ortholog (11) | |||||||||
| Paralog (47) | |||||||||
| Structured_description | Concise_description | msp-113 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-113 has a C. briggsae homolog as detected by the Wobble Aware Bulk Aligner (WABA); the MSP family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; the msp-113 promoter region contains two conserved cis elements that are recognition sites for elt-1, a gene that encodes a homolog of the vertebrate GATA transcription factor family; this suggests that a MSP protein is a potential target for ELT-1 in the germ-line; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. | Paper_evidence | WBPaper00001023 | |||||
| WBPaper00002143 | |||||||||
| WBPaper00003744 | |||||||||
| WBPaper00004280 | |||||||||
| WBPaper00004591 | |||||||||
| WBPaper00005670 | |||||||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 04 May 2005 00:00:00 | ||||||||
| Automated_description | Expressed in gonad; oocyte; and sperm. Is predicted to encode a protein with the following domains: Major sperm protein (MSP) domain; MSP (Major sperm protein) domain; PapD-like superfamily; and Immunoglobulin-like fold. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | ZK354.4 | |||||||
| Corresponding_transcript | ZK354.4.1 | ||||||||
| Other_sequence (15) | |||||||||
| Associated_feature | WBsf996476 | ||||||||
| WBsf1017364 | |||||||||
| WBsf228285 | |||||||||
| Experimental_info | RNAi_result (19) | ||||||||
| Expr_pattern | Expr3417 | ||||||||
| Expr1162790 | |||||||||
| Expr2032005 | |||||||||
| Drives_construct | WBCnstr00036099 | ||||||||
| Construct_product | WBCnstr00036099 | ||||||||
| Antibody | WBAntibody00000037 | ||||||||
| WBAntibody00000038 | |||||||||
| WBAntibody00000854 | |||||||||
| WBAntibody00000855 | |||||||||
| WBAntibody00000856 | |||||||||
| WBAntibody00000857 | |||||||||
| WBAntibody00000858 | |||||||||
| Microarray_results | SMD_ZK354.4 | ||||||||
| A_12_P106610 | |||||||||
| GPL14144_Y59H11AM.1_48-107_0.927_1_A | |||||||||
| GPL8673_ZK354_4P00037 | |||||||||
| Expression_cluster (172) | |||||||||
| Interaction (182) | |||||||||
| Map_info | Map | IV | Position | 1.58867 | Error | 0.00012 | |||
| Positive | Positive_clone | BA#50 | |||||||
| ZK354 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00001023 | ||||||||
| WBPaper00001024 | |||||||||
| WBPaper00003744 | |||||||||
| WBPaper00013809 | |||||||||
| WBPaper00014642 | |||||||||
| WBPaper00015440 | |||||||||
| WBPaper00027309 | |||||||||
| WBPaper00057218 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
