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WormBase Tree Display for Gene: WBGene00003463

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Name Class

WBGene00003463SMapS_parentSequenceZK1251
IdentityVersion1
NameCGC_namemsp-76Person_evidenceWBPerson680
Sequence_nameZK1251.6
Molecular_nameZK1251.6
ZK1251.6.1
CE03853
Other_nameCELE_ZK1251.6Accession_evidenceNDBBX284604
Public_namemsp-76
DB_infoDatabaseAceViewgene4K453
WormQTLgeneWBGene00003463
WormFluxgeneWBGene00003463
NDBlocus_tagCELE_ZK1251.6
NCBIgene177802
RefSeqproteinNM_001380418.1
SwissProtUniProtAccP05634
UniProt_GCRPUniProtAccP05634
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:32WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classmsp
Allele (13)
Legacy_information[C.elegansII] NMK. Encodes MSP (16kD); near msp-56. [Ward et al. (1988); BA]
RNASeq_FPKM (74)
Ortholog (111)
Paralog (49)
Structured_descriptionConcise_descriptionmsp-76 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.Paper_evidenceWBPaper00001023
WBPaper00002143
WBPaper00004591
WBPaper00005670
Curator_confirmedWBPerson324
Date_last_updated31 Mar 2005 00:00:00
Automated_descriptionExpressed in gonad; oocyte; and sperm. Is predicted to encode a protein with the following domains: Major sperm protein (MSP) domain; MSP (Major sperm protein) domain; PapD-like superfamily; and Immunoglobulin-like fold.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSZK1251.6
Corresponding_transcriptZK1251.6.1
Other_sequence (61)
Associated_featureWBsf997464
WBsf1017989
WBsf228859
Experimental_infoRNAi_result (14)
Expr_patternExpr3417
Expr1162619
Expr2013788
Expr2032026
Drives_constructWBCnstr00036104
Construct_productWBCnstr00036104
AntibodyWBAntibody00000037
WBAntibody00000038
WBAntibody00000854
WBAntibody00000855
WBAntibody00000856
WBAntibody00000857
WBAntibody00000858
Microarray_results (17)
Expression_cluster (247)
Interaction (200)
Map_infoMapIVPosition4.35961Error0.001307
PositivePositive_cloneBA#16
ZK1251Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00001023
WBPaper00024312
WBPaper00049828
WBPaper00057218
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene