WormBase Tree Display for Gene: WBGene00003462
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| WBGene00003462 | SMap | S_parent | Sequence | F09C12 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | msp-74 | Person_evidence | WBPerson680 | |||||
| Sequence_name | F09C12.7 | ||||||||
| Molecular_name | F09C12.7 | ||||||||
| F09C12.7.1 | |||||||||
| CE02603 | |||||||||
| Other_name | msp-74ps | ||||||||
| CELE_F09C12.7 | Accession_evidence | NDB | BX284602 | ||||||
| Public_name | msp-74 | ||||||||
| DB_info | Database | AceView | gene | 2F404 | |||||
| WormQTL | gene | WBGene00003462 | |||||||
| WormFlux | gene | WBGene00003462 | |||||||
| NDB | locus_tag | CELE_F09C12.7 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00003462|UniProtKB=G5EEW3 | |||||||
| family | PTHR22920 | ||||||||
| NCBI | gene | 173882 | |||||||
| RefSeq | protein | NM_062548.3 | |||||||
| TrEMBL | UniProtAcc | G5EEW3 | |||||||
| UniProt_GCRP | UniProtAcc | G5EEW3 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:32 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | msp | ||||||||
| Allele | WBVar01499702 | ||||||||
| WBVar01498435 | |||||||||
| WBVar00730107 | |||||||||
| WBVar00730108 | |||||||||
| Legacy_information | [C.elegansII] NMK. Encodes MSP (16kD); near msp-45[Ward et al. (1988); BA] | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00017025 | ||||||||
| 00017026 | |||||||||
| 00017027 | |||||||||
| 00017028 | |||||||||
| 00017029 | |||||||||
| Ortholog (11) | |||||||||
| Paralog (46) | |||||||||
| Structured_description | Concise_description | msp-74 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. | Paper_evidence | WBPaper00001023 | |||||
| WBPaper00002143 | |||||||||
| WBPaper00004591 | |||||||||
| WBPaper00005670 | |||||||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 31 Mar 2005 00:00:00 | ||||||||
| Automated_description | Expressed in gonad; oocyte; and sperm. Is predicted to encode a protein with the following domains: Major sperm protein (MSP) domain; MSP (Major sperm protein) domain; PapD-like superfamily; and Immunoglobulin-like fold. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F09C12.7 | |||||||
| Corresponding_transcript | F09C12.7.1 | ||||||||
| Other_sequence (11) | |||||||||
| Associated_feature | WBsf223000 | ||||||||
| Experimental_info | RNAi_result | WBRNAi00030692 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00017457 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00044086 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00012956 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr3417 | ||||||||
| Expr1016484 | |||||||||
| Expr1148054 | |||||||||
| Drives_construct | WBCnstr00036105 | ||||||||
| Construct_product | WBCnstr00036105 | ||||||||
| Antibody | WBAntibody00000037 | ||||||||
| WBAntibody00000038 | |||||||||
| WBAntibody00000854 | |||||||||
| WBAntibody00000855 | |||||||||
| WBAntibody00000856 | |||||||||
| WBAntibody00000857 | |||||||||
| WBAntibody00000858 | |||||||||
| Microarray_results (15) | |||||||||
| Expression_cluster (138) | |||||||||
| Interaction (214) | |||||||||
| Map_info | Map | II | Position | -2.09141 | |||||
| Positive | Positive_clone | F09C12 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00001023 | ||||||||
| WBPaper00001024 | |||||||||
| WBPaper00014145 | |||||||||
| WBPaper00024312 | |||||||||
| Remark | Merged msp-74ps into msp-74. krb 28/02/02 | ||||||||
| Pseudogene tag removed because the corresponding sequence object for this gene has not been annotated as a pseudogene. This discrepancy may reflect that the sequence object was once a pseudogene and has subsequently been converted into a real gene (without this Locus object being updated). Alternatively it may be that this gene is a pseudogene in another C. elegans strain, but not in the sequenced N2 strain. [krb 030806] | |||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
