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WormBase Tree Display for Gene: WBGene00003424

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Name Class

WBGene00003424SMapS_parentSequenceF26G1
IdentityVersion1
NameCGC_namemsp-3Person_evidenceWBPerson680
Sequence_nameF26G1.7
Molecular_nameF26G1.7
F26G1.7.1
CE02699
Other_nameCELE_F26G1.7Accession_evidenceNDBBX284602
Public_namemsp-3
DB_infoDatabaseAceViewgene2F76
WormFluxgeneWBGene00003424
NDBlocus_tagCELE_F26G1.7
PanthergeneCAEEL|WormBase=WBGene00003424|UniProtKB=Q19832
familyPTHR22920
NCBIgene173825
RefSeqproteinNM_062457.10
SwissProtUniProtAccQ19832
UniProt_GCRPUniProtAccQ19832
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:31WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classmsp
Allele (17)
Legacy_informationCluster of three genes including msp-3 (transcribed).
[C.elegansII] NMK. Encodes major sperm protein MSP (16kD) In cluster of three genes including msp-3. [Ward et al. (1988); BA]
StrainWBStrain00051000
RNASeq_FPKM (74)
GO_annotation00066004
00066005
00066006
00066007
00066008
Ortholog (34)
Paralog (50)
Structured_descriptionConcise_descriptionmsp-3 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-3 is similar in nucleotide sequence to the msp genes from the nematode Onchocerca volvulus; the msp gene family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSP proteins assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.Paper_evidenceWBPaper00001023
WBPaper00001207
WBPaper00002143
WBPaper00004591
WBPaper00005670
Curator_confirmedWBPerson324
Date_last_updated26 Apr 2005 00:00:00
Automated_descriptionPredicted to be located in cytoplasm; cytoskeleton; and pseudopodium. Expressed in gonad; oocyte; and spermatocyte.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF26G1.7
Corresponding_transcriptF26G1.7.1
Other_sequence (17)
Associated_featureWBsf987698
WBsf987699
WBsf987700
WBsf987701
WBsf1012128
WBsf1012129
WBsf222956
Experimental_infoRNAi_resultWBRNAi00092856Inferred_automaticallyRNAi_primary
WBRNAi00022299Inferred_automaticallyRNAi_primary
WBRNAi00092858Inferred_automaticallyRNAi_primary
WBRNAi00103208Inferred_automaticallyRNAi_primary
WBRNAi00013976Inferred_automaticallyRNAi_primary
WBRNAi00041782Inferred_automaticallyRNAi_primary
WBRNAi00045689Inferred_automaticallyRNAi_primary
Expr_patternExpr3417
Expr11147
Expr12948
Expr12949
Expr1149602
Expr2032014
Drives_constructWBCnstr00018185
WBCnstr00036126
Construct_productWBCnstr00036126
AntibodyWBAntibody00000037
WBAntibody00000038
WBAntibody00000854
WBAntibody00000855
WBAntibody00000856
WBAntibody00000857
WBAntibody00000858
Microarray_results (16)
Expression_cluster (233)
Interaction (231)
Map_infoMapIIPosition-3.05828Error0.00639
PositivePositive_cloneBA#59
F26G1Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00001023
WBPaper00001175
WBPaper00001207
WBPaper00004591
WBPaper00024312
WBPaper00025088
WBPaper00040308
WBPaper00041549
WBPaper00049828
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene