WormBase Tree Display for Gene: WBGene00003020
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| WBGene00003020 | SMap | S_parent | Sequence | C32F10 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | lin-35 | Person_evidence | WBPerson261 | |||||
| Sequence_name | C32F10.2 | ||||||||
| Molecular_name | C32F10.2 | ||||||||
| C32F10.2.1 | |||||||||
| CE24823 | |||||||||
| Other_name | CELE_C32F10.2 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | lin-35 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:30 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | lin | ||||||||
| Allele (104) | |||||||||
| Legacy_information | n745 : wildtype alone Muv in homozygotes with lin-8 lin-38 or lin-15(n767). ES2. NA2 (n373 (similar phenotype)). | ||||||||
| See also n373, n745 | |||||||||
| [C.elegansII] n745 : almost WT alone (reduced fertility); Muv (extra vulval differentiation) in homozygotes with lin-8, lin-38 or lin-15(n767). ES2. OA1: n373 (similar). [Ferguson and Horvitz 1989; MT; PS] | |||||||||
| Strain (17) | |||||||||
| Component_of_genotype | WBGenotype00000009 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (50) | |||||||||
| Ortholog (43) | |||||||||
| Structured_description (2) | |||||||||
| Disease_info | Experimental_model | DOID:1059 | Homo sapiens | Paper_evidence | WBPaper00024322 | ||||
| Accession_evidence | OMIM | 309580 | |||||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 18 Apr 2013 00:00:00 | ||||||||
| Potential_model (16) | |||||||||
| Disease_relevance | Human ATRX encodes a protein with a ATPase/helicase domain involved in chromatin remodeling, mutations in which, have been associated with alpha-thalassemia and X-linked mental retardation; the elegans ortholog, xnp-1 is required for gonadal development and acts in association with lin-35/Retinoblastoma (RB), components of the NuRD complex and hpl-2/HP1 genes; the requirement of xnp-1 with lin-35/ Rb in larval development in C. elegans can be compared with the observation that in humans, XNP/ATR-X mutation is also associated, with short stature and skeletal abnormalities during development. | Homo sapiens | Paper_evidence | WBPaper00024322 | |||||
| WBPaper00024692 | |||||||||
| WBPaper00003646 | |||||||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 23 Apr 2013 00:00:00 | ||||||||
| Models_disease_asserted | WBDOannot00000614 | ||||||||
| WBDOannot00001021 | |||||||||
| Molecular_info | Corresponding_CDS | C32F10.2 | |||||||
| Corresponding_transcript | C32F10.2.1 | ||||||||
| Associated_feature | WBsf643315 | ||||||||
| WBsf643316 | |||||||||
| WBsf656335 | |||||||||
| WBsf656336 | |||||||||
| WBsf656337 | |||||||||
| WBsf656338 | |||||||||
| WBsf983774 | |||||||||
| WBsf217712 | |||||||||
| Gene_product_binds (376) | |||||||||
| Transcription_factor | WBTranscriptionFactor000270 | ||||||||
| Experimental_info | RNAi_result (78) | ||||||||
| Expr_pattern | Chronogram622 | ||||||||
| Expr1291 | |||||||||
| Expr3128 | |||||||||
| Expr1015789 | |||||||||
| Expr1031411 | |||||||||
| Expr1145718 | |||||||||
| Expr2013177 | |||||||||
| Expr2031409 | |||||||||
| Drives_construct | WBCnstr00004066 | ||||||||
| WBCnstr00006281 | |||||||||
| WBCnstr00011156 | |||||||||
| WBCnstr00017294 | |||||||||
| WBCnstr00036281 | |||||||||
| Construct_product | WBCnstr00006281 | ||||||||
| WBCnstr00011156 | |||||||||
| WBCnstr00017287 | |||||||||
| WBCnstr00017294 | |||||||||
| WBCnstr00017295 | |||||||||
| WBCnstr00017296 | |||||||||
| WBCnstr00021077 | |||||||||
| WBCnstr00021078 | |||||||||
| WBCnstr00021079 | |||||||||
| WBCnstr00036281 | |||||||||
| Regulate_expr_cluster (16) | |||||||||
| Antibody | WBAntibody00000200 | ||||||||
| WBAntibody00001176 | |||||||||
| WBAntibody00003008 | |||||||||
| WBAntibody00003009 | |||||||||
| Microarray_results (20) | |||||||||
| Expression_cluster (156) | |||||||||
| Interaction (322) | |||||||||
| Product_binds_matrix | WBPmat00005534 | ||||||||
| WBPmat00005535 | |||||||||
| WBPmat00005536 | |||||||||
| WBPmat00005540 | |||||||||
| WBPmat00005541 | |||||||||
| WBPmat00005542 | |||||||||
| WBPmat00005543 | |||||||||
| WBPmat00005544 | |||||||||
| WBPmat00005545 | |||||||||
| Map_info | Map | I | Position | 0.461719 | Error | 0.000997 | |||
| Well_ordered | |||||||||
| Positive | Positive_clone | C32F10 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 283 | |||||||
| 308 | |||||||||
| 309 | |||||||||
| 4517 | |||||||||
| Reference (253) | |||||||||
| Picture | WBPicture0000013091 | ||||||||
| Method | Gene |
