WormBase Tree Display for Gene: WBGene00002324
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| WBGene00002324 | SMap | S_parent | Sequence | Y54E5B | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | let-49 | Person_evidence | WBPerson533 | |||||
| Sequence_name | Y54E5B.3 | ||||||||
| Molecular_name | Y54E5B.3a | ||||||||
| Y54E5B.3a.1 | |||||||||
| CE19227 | |||||||||
| Y54E5B.3b | |||||||||
| CE28136 | |||||||||
| Y54E5B.3b.1 | |||||||||
| Other_name | mdt-7 | ||||||||
| med-7 | |||||||||
| CELE_Y54E5B.3 | Accession_evidence | NDB | BX284601 | ||||||
| Public_name | let-49 | ||||||||
| DB_info | Database | AceView | gene | 1P413 | |||||
| WormQTL | gene | WBGene00002324 | |||||||
| WormFlux | gene | WBGene00002324 | |||||||
| NDB | locus_tag | CELE_Y54E5B.3 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00002324|UniProtKB=Q95Q17 | |||||||
| family | PTHR21428 | ||||||||
| NCBI | gene | 173353 | |||||||
| RefSeq | protein | NM_061184.6 | |||||||
| NM_061185.9 | |||||||||
| SwissProt | UniProtAcc | Q95Q17 | |||||||
| TREEFAM | TREEFAM_ID | TF314411 | |||||||
| UniProt_GCRP | UniProtAcc | Q95Q17 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:27 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | let | ||||||||
| Reference_allele | WBVar00248708 | ||||||||
| Allele (29) | |||||||||
| Legacy_information | st44 : mid-larval lethal. NA1. | ||||||||
| [C.elegansII] st44 : mid-larval lethal. NA1. [Anderson and Brenner 1984; RW] | |||||||||
| Strain | WBStrain00033515 | ||||||||
| WBStrain00051149 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (11) | |||||||||
| Contained_in_operon | CEOP1768 | ||||||||
| Ortholog (35) | |||||||||
| Structured_description | Concise_description | let-49 encodes a putative mediator complex subunit zygotically required for postembryonic development and viability past larval stages, while being maternally required for germline and embryonic development; LET-49 is an ortholog of human CRSP9 (OMIM:605045) and of S. cerevisiae Med7p; Med7p is a component of a mediator complex that serves as a transcriptional coactivator, while CRSP9 mediates transcriptional activation by Sp1. | Paper_evidence | WBPaper00004990 | |||||
| WBPaper00012767 | |||||||||
| WBPaper00013605 | |||||||||
| WBPaper00013623 | |||||||||
| WBPaper00013637 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable transcription coregulator activity. Involved in embryo development and reproduction. Predicted to be located in nucleus. Predicted to be part of core mediator complex and mediator complex. Is an ortholog of human MED7 (mediator complex subunit 7). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | Y54E5B.3a | |||||||
| Y54E5B.3b | |||||||||
| Corresponding_transcript | Y54E5B.3a.1 | ||||||||
| Y54E5B.3b.1 | |||||||||
| Other_sequence (19) | |||||||||
| Associated_feature | WBsf657119 | ||||||||
| WBsf218836 | |||||||||
| Experimental_info | RNAi_result (15) | ||||||||
| Expr_pattern | Expr1027003 | ||||||||
| Expr1031348 | |||||||||
| Expr1160824 | |||||||||
| Expr2013059 | |||||||||
| Expr2031291 | |||||||||
| Drives_construct | WBCnstr00036333 | ||||||||
| Construct_product | WBCnstr00036333 | ||||||||
| Antibody | WBAntibody00001834 | ||||||||
| Microarray_results (26) | |||||||||
| Expression_cluster (89) | |||||||||
| Interaction (81) | |||||||||
| Map_info | Map | I | Position | 27.9112 | Error | 0.091941 | |||
| Positive | Positive_clone | Y54E5B | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | 2_point | 207 | |||||||
| Multi_point | 291 | ||||||||
| 960 | |||||||||
| 2221 | |||||||||
| 4669 | |||||||||
| Pos_neg_data (13) | |||||||||
| Reference (18) | |||||||||
| Method | Gene |
