WormBase Tree Display for Gene: WBGene00002204

WBGene00002204 SMap: S_parent: Sequence: CHROMOSOME_IV
  Identity: Version: 1
    Name: CGC_name: kin-21
      Sequence_name: W08D2.8
      Molecular_name: W08D2.8
        W08D2.8.1
        CE35637
      Other_name: CELE_W08D2.8 Accession_evidence: NDB BX284604
      Public_name: kin-21
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:27 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: kin
    Allele (40)
    Strain: WBStrain00037684
    RNASeq_FPKM (74)
    GO_annotation (15)
    Ortholog (53)
    Paralog (59)
    Structured_description: Automated_description: Predicted to enable protein tyrosine kinase activity. Predicted to be involved in phosphorylation. Human ortholog(s) of this gene implicated in esophagus squamous cell carcinoma; hepatocellular carcinoma; and lung adenocarcinoma. Is an ortholog of human FER (FER tyrosine kinase) and FES (FES proto-oncogene, tyrosine kinase). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:3748 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:3657)
      DOID:3910 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:3657)
      DOID:684 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:3657)
  Molecular_info: Corresponding_CDS: W08D2.8
    Corresponding_CDS_history: W08D2.8:wp109
    Corresponding_transcript: W08D2.8.1
    Other_sequence: OFC01272_1
      JI166602.1
      JO473162.1
      OF00528
      CR08377
      Tcir_isotig17539
      CRC03650_1
    Associated_feature: WBsf997483
      WBsf1018005
      WBsf228882
  Experimental_info: RNAi_result: WBRNAi00109391 Inferred_automatically: RNAi_primary
      WBRNAi00019716 Inferred_automatically: RNAi_primary
      WBRNAi00071714 Inferred_automatically: RNAi_primary
      WBRNAi00109488 Inferred_automatically: RNAi_primary
      WBRNAi00109196 Inferred_automatically: RNAi_primary
      WBRNAi00109585 Inferred_automatically: RNAi_primary
      WBRNAi00071444 Inferred_automatically: RNAi_primary
      WBRNAi00036376 Inferred_automatically: RNAi_primary
      WBRNAi00109294 Inferred_automatically: RNAi_primary
      WBRNAi00054980 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1022036
      Expr1158513
    Drives_construct: WBCnstr00036389
    Construct_product: WBCnstr00036389
    Microarray_results (18)
    Expression_cluster: WBPaper00038438:E.faecalis_24hr_upregulated_RNAseq
      WBPaper00041954:ethanol_upregulated
      WBPaper00042194:nhr-114(RNAi)_upregulated
      WBPaper00042215:wdr-23(tm1817)_upregulated
      WBPaper00042477:rsr-2(RNAi)_downregulated_TilingArray
      WBPaper00044037:eat-2_regulated_nhr-62_dependent
      WBPaper00044037:eat-2_upregulated
      WBPaper00044316:CH3HgCl_7.5uM_upregulated
      WBPaper00044736:rising_dev_expression
      WBPaper00045521:Spermatogenic
      WBPaper00046497:B.thuringiensis_0.1mix_upregulated_12h
      WBPaper00046805:P-granule-RNAi_upregulated_Set1
      WBPaper00048611:MnCl2_downregulated
      WBPaper00049495:starvation-refeeding_regulated
      WBPaper00049498:npr-1(ur89)_regulated_2
      WBPaper00049920:Glucose-Diet_upregulated_N2
      WBPaper00050231:male_enriched
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day1-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053318:Aging_downregulated_mRNA_N2
      WBPaper00053318:mir-71(n4115)_downregulated_mRNA
      WBPaper00053599:female_vs_male_downregulated
      WBPaper00053657:JU2519_M.humicola-infection_24hr
      WBPaper00053810:isp-1(qm150)_downregulated
      WBPaper00053909:N2_vs_CB4856_upregulated
      WBPaper00055226:ADR-2_target_adr-1(tm668)
      WBPaper00055226:ADR-2_target_N2
      WBPaper00055354:Rapamycin-Allantoin_upregulated
      WBPaper00055386:daf-2(e1370)_upregulated
      WBPaper00055386:eat-2(ad465)_upregulated
      WBPaper00055648:sperm_expressed
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00055971:nhl-2(ok818)_20C_downregulated
      WBPaper00055971:nhl-2(ok818)_25C_downregulated
      WBPaper00056090:E.faecalis_upregulated_N2
      WBPaper00056161:male_enriched_siRNA
      WBPaper00056284:ints-1(RNAi)_upregulated
      WBPaper00056290:hsp-6(mg585)_downregulated
      WBPaper00056471:flcn-1(ok975)_downregulated
      WBPaper00056809:smn-1(ok355)_downregulated
      WBPaper00059117:B.subtilis_upregulated
      WBPaper00059426:Ag-nanoparticles_upregulated
      WBPaper00059605:mut-16(pk710)_upregulated
      WBPaper00059987:Wounding_upregulated
      WBPaper00060445:ikb-1(nr2027)_upregulated_L4
      WBPaper00060445:nfki-1(cer1)_ikb-1(nr2027)_upregulated_L4
      WBPaper00060445:nfki-1(cer1)_upregulated_L4
      WBPaper00060683:hlh-11(ko1)_upregulated
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00060909:atfs-1(cmh15)_upregulated
      WBPaper00061007:HB101_upregulated
      WBPaper00061007:S.aquatilis_upregulated
      WBPaper00061081:E.faecalis_upregulated_N2
      WBPaper00061424:Diet_MYb120_upregulated
      WBPaper00061424:Diet_MYb131_upregulated
      WBPaper00061439:unc-30(ok613)_downregulated
      WBPaper00061439:unc-30(ok613)_downregulated_P.aeruginosa-infection
      WBPaper00061479:prg-1(tm872)_upregulated
      WBPaper00061527:C34B2.3_17388-T01C3.5
      WBPaper00062156:jmjd-1.2(zr1010)_upregulated
      WBPaper00062156:jmjd-5(zr1234)_upregulated
      WBPaper00062456:doxycycline_upregulated_N2_transcript
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064130:Beta-Amyloid_24h_upregulated_mRNA
      WBPaper00064539:nhr-114(gk849)_downregulated
      WBPaper00064716:paraquat_downregulated
      WBPaper00065005:sams-3(RNAi)_upregulated
      WBPaper00065096:25C_vs_20C_downregulated
      WBPaper00065096:Day10_vs_Day1_downregulated
      WBPaper00065096:npr-8(ok1439)_upregulated_Day1_25C
      WBPaper00065096:npr-8(ok1439)_upregulated_Day10_20C
      WBPaper00065096:npr-8(ok1439)_upregulated_Day10_25C
      WBPaper00065258:anchor-cell_enriched
      WBPaper00065984:pals-17(syb3980)_upregulated
      WBPaper00066038:mip-1(how5)_upregulated
      WBPaper00066085:hda-3(ok1991)_upregulated
      WBPaper00066110:Cisplatin_upregulated_diploid
      WBPaper00066110:Doxorubicin_upregulated_diploid
      WBPaper00066110:tetraploid_vs_diploid_upregulated
      WBPaper00066232:ash-2(RNAi)_downregulated_WT
      cgc4489_group_14
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00038172:aak-2overexpression_up_regulated
      WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_24h
      WBPaper00045263:0.1mM-paraquat_downregulated
      WBPaper00045263:isp-1(qm150)_downregulated
      WBPaper00045263:nuo-6(qm200)_downregulated
      WBPaper00045263:ProLongevity-mtROS_downregulated
      WBPaper00045673:colistin_downregulated
      WBPaper00048989:N2_rapamycin_upregulated
      [cgc6390]:spermatogenesis-enriched
    Interaction: WBInteraction000030950
      WBInteraction000325032
      WBInteraction000390918
      WBInteraction000414141
      WBInteraction000503273
      WBInteraction000547422
  Map_info: Map: IV Position: 4.43023 Error: 0.000599
    Positive: Positive_clone: W08D2 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00003205
    WBPaper00027258
    WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene