WormBase Tree Display for Gene: WBGene00002191
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| WBGene00002191 | Evidence | Person_evidence | WBPerson1698 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | B0205 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | kin-3 | |||||||
| Sequence_name | B0205.7 | ||||||||
| Molecular_name | B0205.7 | ||||||||
| B0205.7.1 | |||||||||
| CE17321 | |||||||||
| Other_name | CKIIalpha | Paper_evidence | WBPaper00001380 | ||||||
| casein kinase II | Paper_evidence | WBPaper00051123 | |||||||
| CELE_B0205.7 | Accession_evidence | NDB | BX284601 | ||||||
| Public_name | kin-3 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:27 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | kin | ||||||||
| Allele (39) | |||||||||
| Possibly_affected_by | WBVar02157787 | ||||||||
| Legacy_information | [C.elegansII] NMK. Encodes casein kinase II alpha. Not located on physical map (clone CR#G1, Y42G4, Y52D1). [CR] | ||||||||
| Strain | WBStrain00036179 | ||||||||
| WBStrain00036321 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (43) | |||||||||
| Contained_in_operon | CEOP1644 | ||||||||
| Ortholog (48) | |||||||||
| Structured_description | Concise_description | kin-3 encodes an ortholog of the catalytic subunit of casein kinase II alpha, which in Drosophila and mammals is required for normal circadian rhythms, and which directly phosphorylates the Drosophila PERIOD protein (which itself regulates circadian rhythms); by analogy, KIN-3 might be expected to help regulate heterochronic functions dependent on such proteins as LIN-42. | Paper_evidence | WBPaper00013178 | |||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Enables protein serine/threonine kinase activity. Involved in response to hermaphrodite contact and vulval location. Located in neuronal cell body; nucleus; and plasma membrane bounded cell projection. Part of protein kinase CK2 complex. Expressed in oocyte. Human ortholog(s) of this gene implicated in breast cancer. Is an ortholog of human CSNK2A1 (casein kinase 2 alpha 1) and CSNK2A3 (casein kinase 2 alpha 3). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:1612 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2457) | ||||
| Molecular_info | Corresponding_CDS | B0205.7 | |||||||
| Corresponding_transcript | B0205.7.1 | ||||||||
| Other_sequence (133) | |||||||||
| Associated_feature | WBsf643712 | ||||||||
| WBsf656897 | |||||||||
| WBsf656898 | |||||||||
| WBsf218481 | |||||||||
| WBsf218482 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00069887 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00027978 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00108298 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00038709 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00108259 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00069892 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00069888 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00069893 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00069889 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1394 | ||||||||
| Expr7817 | |||||||||
| Expr12664 | |||||||||
| Expr13057 | |||||||||
| Expr16027 | |||||||||
| Expr1018488 | |||||||||
| Expr1031284 | |||||||||
| Expr1142918 | |||||||||
| Expr2012942 | |||||||||
| Expr2031174 | |||||||||
| Drives_construct | WBCnstr00022270 | ||||||||
| WBCnstr00036399 | |||||||||
| Construct_product | WBCnstr00012942 | ||||||||
| WBCnstr00014880 | |||||||||
| WBCnstr00022270 | |||||||||
| WBCnstr00036399 | |||||||||
| Antibody | WBAntibody00001769 | ||||||||
| WBAntibody00002674 | |||||||||
| WBAntibody00002715 | |||||||||
| Microarray_results (21) | |||||||||
| Expression_cluster (121) | |||||||||
| Interaction (347) | |||||||||
| WBProcess | WBbiopr:00000012 | ||||||||
| Map_info | Map | I | Position | 5.07446 | Error | 0.00292 | |||
| Positive | Positive_clone | B0205 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| CR#G1 | |||||||||
| Mapping_data | Multi_point | 4913 | |||||||
| Pseudo_map_position | |||||||||
| Reference (21) | |||||||||
| Remark | Locus-sequence connection is based on B0205.7 encoding the only casein kinase II alpha in the genome | Person_evidence | WBPerson1698 | ||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
