WormBase Tree Display for Gene: WBGene00002174
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| WBGene00002174 | Evidence | CGC_data_submission | |||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | W03D8 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | itx-1 | |||||||
| Sequence_name | W03D8.6 | ||||||||
| Molecular_name (15) | |||||||||
| Other_name | CELE_W03D8.6 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | itx-1 | ||||||||
| DB_info | Database | AceView | gene | 1D383 | |||||
| WormQTL | gene | WBGene00002174 | |||||||
| WormFlux | gene | WBGene00002174 | |||||||
| NDB | locus_tag | CELE_W03D8.6 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00002174|UniProtKB=O45000 | |||||||
| family | PTHR15036 | ||||||||
| NCBI | gene | 171846 | |||||||
| RefSeq | protein | NM_001306454.3 | |||||||
| NM_001306455.3 | |||||||||
| NM_001262315.4 | |||||||||
| NM_001306453.2 | |||||||||
| NM_001262316.5 | |||||||||
| TREEFAM | TREEFAM_ID | TF321823 | |||||||
| TrEMBL | UniProtAcc | O45000 | |||||||
| A0A078BS63 | |||||||||
| A0A078BPL3 | |||||||||
| A0A078BPJ4 | |||||||||
| H1ZUX6 | |||||||||
| UniProt_GCRP | UniProtAcc | O45000 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:26 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | itx | ||||||||
| Allele (359) | |||||||||
| Strain | WBStrain00037747 | ||||||||
| In_cluster | conserved_miRNA_siRNA_cluster | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00000447 | ||||||||
| 00021312 | |||||||||
| 00021313 | |||||||||
| Ortholog (30) | |||||||||
| Paralog (50) | |||||||||
| Structured_description | Concise_description | itx-1 encodes one of two Caspr orthologues found in the C. elegans genome; Caspr proteins belong to the Neurexin superfamily and are involved in mediating cell-cell contacts and in the formation of specialized membrane-domains in polarized epithelial and nerve cells; RNA interference of itx-1 suggests that itx-1 is involved in the correct positioning and maintenance of apical junctions and in maintaining epithelial integrity in the gut; gfp-reporter studies indicate that ITX-1 is expressed in intestinal cell epithelia and in the socket cells of the inner and outer labial sensilla; immunofluorescence studies indicate that ITX-1 localizes to the baso-lateral membranes of intestinal epithelia. | Paper_evidence | WBPaper00018360 | |||||
| WBPaper00019572 | |||||||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 24 Jan 2005 00:00:00 | ||||||||
| Automated_description | Located in adherens junction and basolateral plasma membrane. Expressed in anterior ganglion; intestine; spermatheca; and vulval muscle. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | W03D8.6a | |||||||
| W03D8.6b | |||||||||
| W03D8.6c | |||||||||
| W03D8.6d | |||||||||
| W03D8.6e | |||||||||
| Corresponding_CDS_history | W03D8.6:wp86 | ||||||||
| W03D8.6:wp156 | |||||||||
| W03D8.6a:wp244 | |||||||||
| W03D8.6b:wp244 | |||||||||
| Corresponding_transcript | W03D8.6a.1 | ||||||||
| W03D8.6b.1 | |||||||||
| W03D8.6c.1 | |||||||||
| W03D8.6d.1 | |||||||||
| W03D8.6e.1 | |||||||||
| Other_sequence | JI474998.1 | ||||||||
| EX547580.1 | |||||||||
| ACC16194_1 | |||||||||
| Acan_isotig15555 | |||||||||
| JI477279.1 | |||||||||
| JI482191.1 | |||||||||
| Associated_feature (11) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00004392 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00054687 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00036229 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00115344 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr9160 | ||||||||
| Expr9162 | |||||||||
| Expr1013654 | |||||||||
| Expr1031269 | |||||||||
| Expr1158225 | |||||||||
| Expr2012877 | |||||||||
| Expr2031111 | |||||||||
| Drives_construct | WBCnstr00013757 | ||||||||
| WBCnstr00036409 | |||||||||
| Construct_product | WBCnstr00036409 | ||||||||
| Antibody | WBAntibody00002166 | ||||||||
| Microarray_results (20) | |||||||||
| Expression_cluster (171) | |||||||||
| Interaction (16) | |||||||||
| Map_info | Map | I | Position | -6.26431 | Error | 0.451296 | |||
| Positive | Positive_clone | W03D8 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4915 | |||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00018360 | ||||||||
| WBPaper00019572 | |||||||||
| WBPaper00025183 | |||||||||
| WBPaper00037763 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00061547 | |||||||||
| Remark | Sequence connection from [Haklai-Topper L] | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
