WormBase Tree Display for Gene: WBGene00002149
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WBGene00002149 | SMap | S_parent | Sequence | CHROMOSOME_X | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 1 | |||||||
Name | CGC_name | irk-1 | Person_evidence | WBPerson655 | |||||
Sequence_name | R03E9.4 | ||||||||
Molecular_name | R03E9.4 | ||||||||
R03E9.4.1 | |||||||||
CE47227 | |||||||||
R03E9.4.2 | |||||||||
Other_name | irk-4 | ||||||||
CELE_R03E9.4 | Accession_evidence | NDB | BX284606 | ||||||
Public_name | irk-1 | ||||||||
DB_info | Database | AceView | gene | XH386 | |||||
WormQTL | gene | WBGene00002149 | |||||||
WormFlux | gene | WBGene00002149 | |||||||
NDB | locus_tag | CELE_R03E9.4 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00002149|UniProtKB=P52192 | |||||||
family | PTHR11767 | ||||||||
NCBI | gene | 180944 | |||||||
RefSeq | protein | NM_076737.5 | |||||||
SwissProt | UniProtAcc | P52192 | |||||||
UniProt_GCRP | UniProtAcc | P52192 | |||||||
OMIM | gene | 600681 | |||||||
600734 | |||||||||
600937 | |||||||||
613236 | |||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:26 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | irk | ||||||||
Allele (170) | |||||||||
Legacy_information | [Thomas JH] irk for Inward Rectifying potassium (K) channel family. | ||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (22) | |||||||||
Ortholog (60) | |||||||||
Paralog | WBGene00002150 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
Panther | |||||||||
WormBase-Compara | |||||||||
WBGene00002151 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
Panther | |||||||||
WormBase-Compara | |||||||||
Structured_description | Automated_description | Enables inward rectifier potassium channel activity. Involved in regulation of G protein-coupled receptor signaling pathway and regulation of egg-laying behavior. Located in neuron projection and neuronal cell body. Expressed in egg-laying apparatus; gonad; intestine; and neurons. Human ortholog(s) of this gene implicated in several diseases, including glucose metabolism disease (multiple); heart conduction disease (multiple); and long QT syndrome (multiple). Is an ortholog of several human genes including KCNJ2 (potassium inwardly rectifying channel subfamily J member 2); KCNJ3 (potassium inwardly rectifying channel subfamily J member 3); and KCNJ4 (potassium inwardly rectifying channel subfamily J member 4). | Paper_evidence | WBPaper00065943 | |||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model (16) | ||||||||
Molecular_info | Corresponding_CDS | R03E9.4 | |||||||
Corresponding_CDS_history | R03E9.4:wp230 | ||||||||
Corresponding_transcript | R03E9.4.1 | ||||||||
R03E9.4.2 | |||||||||
Other_sequence (14) | |||||||||
Associated_feature | WBsf1005634 | ||||||||
WBsf1005635 | |||||||||
WBsf1005636 | |||||||||
WBsf1005637 | |||||||||
WBsf1005638 | |||||||||
WBsf1005639 | |||||||||
WBsf1005640 | |||||||||
WBsf1023138 | |||||||||
WBsf1023139 | |||||||||
Experimental_info | RNAi_result | WBRNAi00051184 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00017358 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Expr10594 | ||||||||
Expr16175 | |||||||||
Expr1023014 | |||||||||
Expr1154892 | |||||||||
Expr2012823 | |||||||||
Expr2031061 | |||||||||
Drives_construct | WBCnstr00015669 | ||||||||
WBCnstr00017021 | |||||||||
WBCnstr00042792 | |||||||||
Construct_product | WBCnstr00015618 | ||||||||
WBCnstr00015670 | |||||||||
WBCnstr00015671 | |||||||||
WBCnstr00015672 | |||||||||
WBCnstr00015673 | |||||||||
WBCnstr00017021 | |||||||||
WBCnstr00042792 | |||||||||
Microarray_results (22) | |||||||||
Expression_cluster (103) | |||||||||
Interaction (29) | |||||||||
Map_info | Map | X | Position | -2.44289 | Error | 0.004144 | |||
Positive | Positive_clone | R03E9 | Person_evidence | WBPerson654 | |||||
WBPerson655 | |||||||||
Inferred_automatically | From sequence, transcript, pseudogene data | ||||||||
Pseudo_map_position | |||||||||
Reference | WBPaper00006402 | ||||||||
WBPaper00028146 | |||||||||
WBPaper00034195 | |||||||||
WBPaper00038491 | |||||||||
WBPaper00041734 | |||||||||
WBPaper00049295 | |||||||||
WBPaper00055090 | |||||||||
WBPaper00060042 | |||||||||
WBPaper00064330 | |||||||||
Remark | irk-4 is the same as irk-1. Both Loci have now been merged into irk-1 with irk-4 just becoming an Other_name for this loci [krb 28/01/02] | ||||||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
Method | Gene |