WormBase Tree Display for Gene: WBGene00002068
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| WBGene00002068 | Evidence | Paper_evidence | WBPaper00005604 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | C27A2 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | ify-1 | Person_evidence | WBPerson533 | |||||
| Sequence_name | C27A2.3 | ||||||||
| Molecular_name | C27A2.3 | ||||||||
| C27A2.3.1 | |||||||||
| CE04103 | |||||||||
| Other_name | CELE_C27A2.3 | Accession_evidence | NDB | BX284602 | |||||
| Public_name | ify-1 | ||||||||
| DB_info | Database | AceView | gene | 2F344 | |||||
| WormQTL | gene | WBGene00002068 | |||||||
| WormFlux | gene | WBGene00002068 | |||||||
| NDB | locus_tag | CELE_C27A2.3 | |||||||
| NCBI | gene | 173872 | |||||||
| RefSeq | protein | NM_062530.11 | |||||||
| SwissProt | UniProtAcc | Q18235 | |||||||
| TREEFAM | TREEFAM_ID | TF318045 | |||||||
| UniProt_GCRP | UniProtAcc | Q18235 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:26 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | ify | ||||||||
| Allele (18) | |||||||||
| Strain | WBStrain00054984 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (27) | |||||||||
| Ortholog (23) | |||||||||
| Structured_description | Concise_description | ify-1 encodes a rapidly evolving protein ligand of FZY-1, with only 53% identity between C. elegans and C. briggsae and with no visible homologs in more distant species; IFY-1 binds FZY-1 and SEP-1 in yeast two-hybrid assays; ify-1(RNAi) and sep-1(RNAi) animals arrest as one-cell embryos with disorganized chromosomes, supporting the hypothesis that IFY-1 is a securin; the fzy-1(h1983) mutation blocks FZY-1 binding to IFY-1, but not to MDF-2, another possible FZY-1 ligand; IFY-1 protein accumulates abnormally in developmentally arrested one-cell emb-30 embryos. | Paper_evidence | WBPaper00005604 | |||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 02 Oct 2006 00:00:00 | ||||||||
| Automated_description | Enables protease binding activity and ubiquitin protein ligase binding activity. Involved in several processes, including cortical granule exocytosis; nuclear division; and protein stabilization. Located in condensed chromosome; cytoplasm; and spindle microtubule. Expressed in germ cell. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | C27A2.3 | |||||||
| Corresponding_transcript | C27A2.3.1 | ||||||||
| Other_sequence | FD514623.1 | ||||||||
| CBC03920_1 | |||||||||
| CSC01498_1 | |||||||||
| Associated_feature | WBsf650034 | ||||||||
| WBsf650035 | |||||||||
| WBsf987790 | |||||||||
| WBsf1012176 | |||||||||
| WBsf222993 | |||||||||
| WBsf222994 | |||||||||
| Experimental_info | RNAi_result (38) | ||||||||
| Expr_pattern | Expr10983 | ||||||||
| Expr1022694 | |||||||||
| Expr1031221 | |||||||||
| Expr1145344 | |||||||||
| Expr1200196 | |||||||||
| Expr2012702 | |||||||||
| Expr2030938 | |||||||||
| Drives_construct | WBCnstr00017597 | ||||||||
| WBCnstr00036479 | |||||||||
| Construct_product | WBCnstr00009266 | ||||||||
| WBCnstr00017307 | |||||||||
| WBCnstr00017597 | |||||||||
| WBCnstr00017616 | |||||||||
| WBCnstr00036479 | |||||||||
| Antibody | WBAntibody00000990 | ||||||||
| Microarray_results (17) | |||||||||
| Expression_cluster (216) | |||||||||
| Interaction (98) | |||||||||
| Map_info | Map | II | Position | -2.58429 | Error | 0.001659 | |||
| Positive | Positive_clone | C27A2 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Pseudo_map_position | |||||||||
| Reference (16) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
