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WormBase Tree Display for Gene: WBGene00002064

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Name Class

WBGene00002064SMapS_parentSequenceT05G5
IdentityVersion1
NameCGC_nameiff-1Person_evidenceWBPerson284
Sequence_nameT05G5.10
Molecular_nameT05G5.10a
T05G5.10a.1
CE37787
T05G5.10b
CE00503
T05G5.10c
CE46328
T05G5.10b.1
T05G5.10c.1
Other_nameCELE_T05G5.10Accession_evidenceNDBBX284603
Public_nameiff-1
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:26WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classiff
Allele (19)
StrainWBStrain00022686
WBStrain00022688
RNASeq_FPKM (74)
GO_annotation (24)
Ortholog (38)
ParalogWBGene00002065Caenorhabditis elegansFrom_analysisInparanoid_8
Panther
WormBase-Compara
Structured_descriptionConcise_descriptioniff-1 encodes an eIF-5A homolog that affects fertility and is required for germ cell proliferation and for some P granule components to localize properly; expression is germline specific and mRNA is expressed in the distal region of gonads where germ cells actively proliferate.Paper_evidenceWBPaper00012310
WBPaper00018717
Curator_confirmedWBPerson48
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable translation elongation factor activity. Involved in gamete generation and protein localization. Predicted to be located in cytoplasm. Expressed in germ line and gonad. Human ortholog(s) of this gene implicated in colorectal cancer. Is an ortholog of human EIF5A (eukaryotic translation initiation factor 5A).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:9256Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:3300)
Molecular_infoCorresponding_CDST05G5.10a
T05G5.10b
T05G5.10c
Corresponding_CDS_historyT05G5.10:wp135
Corresponding_transcriptT05G5.10a.1
T05G5.10b.1
T05G5.10c.1
Other_sequence (107)
Associated_featureWBsf651400
WBsf667319
WBsf667320
WBsf993786
WBsf1015666
Experimental_infoRNAi_result (15)
Expr_patternExpr2909
Expr2911
Expr2912
Expr1021225
Expr1031217
Expr1156177
Expr2012691
Expr2030927
Drives_constructWBCnstr00036483
Construct_productWBCnstr00036483
Regulate_expr_clusterWBPaper00057288:iff-1(RNAi)_downregulated_transcript
WBPaper00057288:iff-1(RNAi)_upregulated_protein
WBPaper00057288:iff-1(RNAi)_upregulated_transcript
AntibodyWBAntibody00000726
Microarray_results (23)
Expression_cluster (235)
Interaction (346)
Map_infoMapIIIPosition0.949142Error0.006732
PositivePositive_cloneT05G5Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4195
4435
Pseudo_map_position
Reference (15)
RemarkSequence connection from [Iino Y]
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene