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WormBase Tree Display for Gene: WBGene00002015

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Name Class

WBGene00002015SMapS_parentSequenceT27E4
IdentityVersion1
NameCGC_namehsp-16.1Person_evidenceWBPerson36
Sequence_nameT27E4.8
Molecular_nameT27E4.8
T27E4.8.1
CE14249
Other_namehsp-16
CELE_T27E4.8Accession_evidenceNDBBX284605
Public_namehsp-16.1
DB_infoDatabaseAceViewgene5J568
WormQTLgeneWBGene00002015
WormFluxgeneWBGene00002015
NDBlocus_tagCELE_T27E4.8
PanthergeneCAEEL|WormBase=WBGene00002015|UniProtKB=P34696
familyPTHR45640
NCBIgene179286
RefSeqproteinNM_072953.5
SwissProtUniProtAccP34696
UniProt_GCRPUniProtAccP34696
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:26WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_info (10)
Disease_infoDisease_relevanceC. elegans is an effective model system to study heat-related pathologies like heat stroke; in elegans, a small heat shock protein (sHSP), HSP-16.1 has a protective effect against heat-induced necrosis; HSP-16.1 localizes to the golgi and functions together with the PMR-1/PMR1 Ca2+ and Mn2+ transporting ATPase, and NUCB-1/Nucleobindin1, a golgi-located calcium-buffering protein, to maintain calcium homeostasis, under heat stroke; overexpresiion of pmr-1/PMR1 is sufficient to promote survival after heat stroke, bypassing both HSF-1 and HSP-16.1, indicating that PMR-1/PMR1 functions downstream of both these genes.Homo sapiensPaper_evidenceWBPaper00041564
Curator_confirmedWBPerson324
Date_last_updated29 May 2013 00:00:00
Molecular_infoCorresponding_CDST27E4.8
Corresponding_transcriptT27E4.8.1
Other_sequence (60)
Associated_featureWBsf977958Paper_evidenceWBPaper00000918
WBsf977959Paper_evidenceWBPaper00000918
WBsf977962
WBsf1000813
WBsf234177
WBsf234178
Experimental_infoRNAi_result (21)
Expr_patternExpr1381
Expr1384
Expr10597
Expr11025
Expr15516
Expr1157862
Expr2012617
Expr2030853
Drives_construct (37)
Construct_productWBCnstr00010254
WBCnstr00017024
WBCnstr00019264
WBCnstr00036521
WBCnstr00042207
AntibodyWBAntibody00000049
WBAntibody00001859
Microarray_resultsSMD_T27E4.8
189087_s_at
A_12_P110679
Aff_T27E4.2
GPL13394_WBGene00002017
GPL13914_T27E4.2
GPL14144_T27E4.2_171-230_0.514_60_C
GPL14144_T27E4.2_262-321_0.911_1_A
GPL14144_T27E4.2_378-437_0.692_33_B
GPL19516_CGZ0037146
GPL19516_CGZ0037153
GPL21109_T27E4.2
GPL3518_CE14249
GPL8304_CE_WBGene00002015_A
GPL8304_CE_WBGene00002015_C
GPL8304_CE_WBGene00002017_A
GPL8673_T27E4_2P00061
GPL8673_T27E4_2P00134
GPL8673_T27E4_2P00361
GPL8673_T27E4_8P00061
GPL8673_T27E4_8P00134
GPL8673_T27E4_8P00361
GPL9450_T27E4.2_92
GPL9450_T27E4.8_92
Expression_cluster (245)
Interaction (92)
WBProcessWBbiopr:00000050
Map_infoMapVPosition1.9236Error0.000891
PositivePositive_cloneT27E4Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point4419
5342
Pseudo_map_position
Reference (121)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene