WormBase Tree Display for Gene: WBGene00002005
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| WBGene00002005 | SMap | S_parent | Sequence | F26D10 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | hsp-1 | Person_evidence | WBPerson36 | |||||
| Sequence_name | F26D10.3 | ||||||||
| Molecular_name | F26D10.3 | ||||||||
| F26D10.3.1 | |||||||||
| CE09682 | |||||||||
| Other_name | hsp70cB | Paper_evidence | WBPaper00064398 | ||||||
| CELE_F26D10.3 | Accession_evidence | NDB | BX284604 | ||||||
| Public_name | hsp-1 | ||||||||
| DB_info | Database | AceView | gene | 4S223 | |||||
| WormQTL | gene | WBGene00002005 | |||||||
| WormFlux | gene | WBGene00002005 | |||||||
| NDB | locus_tag | CELE_F26D10.3 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00002005|UniProtKB=P09446 | |||||||
| family | PTHR19375 | ||||||||
| NCBI | gene | 178507 | |||||||
| RefSeq | protein | NM_070667.7 | |||||||
| SwissProt | UniProtAcc | P09446 | |||||||
| UniProt_GCRP | UniProtAcc | P09446 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:26 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | hsp | ||||||||
| Allele (70) | |||||||||
| Legacy_information | [C.elegansII] NMK. Encodes protein related to generic hsp70. Quite strong expression normally, only weak heat shock induction. [Heschl and Baillie 1990; BC] | ||||||||
| Strain | WBStrain00037793 | ||||||||
| WBStrain00005873 | |||||||||
| WBStrain00005874 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (28) | |||||||||
| Ortholog (90) | |||||||||
| Paralog (12) | |||||||||
| Structured_description | Concise_description | hsp-1 encodes hsp70A, a member of the heat shock family of proteins; hsp70A is closely related to the Drosophila heat inducible hsp70s and the S. cerevisiae SSA hsp70 subfamily; the hsp-1 gene is normally expressed throughout development and upon heat-shock the hsp-1 mRNA is enhanced 2-6 fold; down-regulation of hsp-1 via RNA interference results in a small reduction in the life-span of an age-1 mutant indicating that hsp-1 may play some role in regulating longevity. | Paper_evidence | WBPaper00001048 | |||||
| WBPaper00001320 | |||||||||
| WBPaper00006377 | |||||||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Enables ATP hydrolysis activity. Involved in determination of adult lifespan; response to heat; and retrograde transport, endosome to Golgi. Located in cytosol and nucleus. Expressed in germ line and intestine. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; autoimmune disease (multiple); brain disease (multiple); and eye disease (multiple). Is an ortholog of human HSPA8 (heat shock protein family A (Hsp70) member 8). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model (35) | ||||||||
| Molecular_info | Corresponding_CDS | F26D10.3 | |||||||
| Corresponding_transcript | F26D10.3.1 | ||||||||
| Other_sequence (757) | |||||||||
| Associated_feature (19) | |||||||||
| Experimental_info | RNAi_result (52) | ||||||||
| Expr_pattern | Expr563 | ||||||||
| Expr5873 | |||||||||
| Expr14424 | |||||||||
| Expr1014885 | |||||||||
| Expr1031170 | |||||||||
| Expr1149522 | |||||||||
| Expr2012623 | |||||||||
| Expr2030859 | |||||||||
| Drives_construct | WBCnstr00002042 | ||||||||
| WBCnstr00036527 | |||||||||
| WBCnstr00040854 | |||||||||
| Construct_product | WBCnstr00016264 | ||||||||
| WBCnstr00036527 | |||||||||
| Antibody | WBAntibody00002793 | ||||||||
| Microarray_results (28) | |||||||||
| Expression_cluster (248) | |||||||||
| Interaction (414) | |||||||||
| WBProcess | WBbiopr:00000039 | ||||||||
| Map_info | Map | IV | Position | 16.3526 | Error | 0.011292 | |||
| Well_ordered | |||||||||
| Positive | Positive_clone | F26D10 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| HSL151 | |||||||||
| Mapping_data | 2_point | 4670 | |||||||
| 4674 | |||||||||
| Multi_point | 1124 | ||||||||
| 4164 | |||||||||
| 4677 | |||||||||
| 5557 | |||||||||
| Pos_neg_data | 4675 | ||||||||
| Landmark_gene | |||||||||
| Reference (62) | |||||||||
| Method | Gene |
