WormBase Tree Display for Gene: WBGene00001915

WBGene00001915 SMap: S_parent: Sequence: C50F4
  Identity: Version: 1
    Name: CGC_name: his-41 Person_evidence: WBPerson160
      Sequence_name: C50F4.5
      Molecular_name: C50F4.5
        C50F4.5.1
        CE05470
      Other_name: CELE_C50F4.5 Accession_evidence: NDB BX284605
      Public_name: his-41
    DB_info: Database: AceView gene 5K25
        WormQTL gene WBGene00001915
        WormFlux gene WBGene00001915
        NDB locus_tag CELE_C50F4.5
        Panther gene CAEEL|WormBase=WBGene00001915|UniProtKB=Q27484
          family PTHR23428
        NCBI gene 179340
        RefSeq protein NM_073063.6
        SwissProt UniProtAcc Q27484
        UniProt_GCRP UniProtAcc Q27484
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:26 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: his
    Allele (19)
    RNASeq_FPKM (74)
    GO_annotation (12)
    Ortholog (182)
    Paralog (16)
    Structured_description: Concise_description: his-41 encodes an H2B histone. Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable DNA binding activity. Predicted to be located in chromosome and nucleus. Predicted to be part of nucleosome. Is an ortholog of several human genes including H2BC3 (H2B clustered histone 3); H2BC5 (H2B clustered histone 5); and H2BC8 (H2B clustered histone 8). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: C50F4.5
    Corresponding_transcript: C50F4.5.1
    Associated_feature: WBsf647086
      WBsf647087
      WBsf661570
      WBsf981978
      WBsf1000931
      WBsf1020196
      WBsf232268
  Experimental_info: RNAi_result (12)
    Expr_pattern: Expr5561
      Expr1022052
      Expr1031121
      Expr1146914
      Expr2012458
      Expr2030694
    Drives_construct: WBCnstr00004048
      WBCnstr00036600
    Construct_product: WBCnstr00036600
    Microarray_results (20)
    Expression_cluster: WBPaper00035269:cde-1_regulated
      WBPaper00037055:DAF-16_binding_DNA
      WBPaper00037682:sma-2_sma-4_upregulated
      WBPaper00037950:all-neurons_L2-larva_expressed
      WBPaper00037950:dopaminergic-neurons_larva_enriched
      WBPaper00037950:dopaminergic-neurons_larva_SelectivelyEnriched
      WBPaper00037950:hypodermis_larva_enriched
      WBPaper00037950:hypodermis_larva_SelectivelyEnriched
      WBPaper00038289:oocyte_protein
      WBPaper00038438:E.faecalis_24hr_downregulated_RNAseq
      WBPaper00044736:flat_dev_expression
      WBPaper00044786:emr-1(gk119)_upregulated
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
      WBPaper00045861:set-2(ok952)_upregulated
      WBPaper00045861:wdr-5(ok1417)_upregulated
      WBPaper00045974:NSM_enriched_totalRNA_RNAseq
      WBPaper00045974:NSM_enriched_totalRNA_tiling
      WBPaper00046303:P.aeruginosa_downregulated_protein
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
      WBPaper00048923:Aging_regulated
      WBPaper00048988:neuron_enriched
      WBPaper00048988:neuron_expressed
      WBPaper00049495:starvation-refeeding_regulated
      WBPaper00049545:cco-1(RNAi)_downregulated
      WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_downregulated
      WBPaper00049942:HeatShock_upregulated_hsf-1(+)
      WBPaper00050163:chd-3(eh4);let-418(RNAi)_upregulated_24-cell-embryo
      WBPaper00050163:chd-3(eh4);let-418(RNAi)_upregulated_100-cell-embryo
      WBPaper00050344:AFD-neuron_enriched
      WBPaper00050344:ASER-neuron_enriched
      WBPaper00050344:PLM-neuron_enriched
      WBPaper00050488:20C_vs_25C_regulated_mir-34(gk437)_adult
      WBPaper00050488:20C_vs_25C_regulated_mir-34(OverExpression)_adult
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050686:glp-1(e2141)_downregulated
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day1-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00051039:intestine_enriched
      WBPaper00052868:ALA_downregulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053388:dauer_regulated_Cluster5
      WBPaper00053814:15C_downregulated_OP50
      WBPaper00053814:15C_downregulated_PY79
      WBPaper00054191:H3.3(null)_L1_downregulated
      WBPaper00055013:HMG-4_interacting_protein
      WBPaper00055354:eat-2(ad1116)_downregulated
      WBPaper00055482:Tunicamycin_downregulated
      WBPaper00055897:heat-shock_upregulated
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056139:soil-microbiota_upregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00056471:S.aureus-4h_downregulated_N2
      WBPaper00056809:smn-1(ok355)_upregulated
      WBPaper00056826:SGP_biased
      WBPaper00057140:meg-3(tm4259)_meg-4(ax2026)_upregulated
      WBPaper00057140:pptr-1(tm3103)_upregulated
      WBPaper00057154:HeatShock_upregulated_mRNA
      WBPaper00057288:Cold_downregulated_protein
      WBPaper00057288:Cold_upregulated_transcript
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058598:spn-4(tm291)_upregulated
      WBPaper00058691:cfp-1(tm6369)_upregulated
      WBPaper00058691:set-2(bn129)_upregulated
      WBPaper00058691:sin-3(tm1276)_downregulated
      WBPaper00058948:PA14_downregulated
      WBPaper00058955:heatshock_upregulated_CE
      WBPaper00059356:BAZ-2_SET-6_interacting
      WBPaper00059471:EGL-43_interacting
      WBPaper00059598:HeatShock_upregulated
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00059763:neuron_expressed
      WBPaper00059824:rnp-6(dh1127)_regulated_S.aureus
      WBPaper00059895:wounding_upregulated
      WBPaper00060661:sensory-neuron_enriched
      WBPaper00060811:L1_vs_adult_upregulated_neural
      WBPaper00061203:let-418(n3536)_upregulated
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061340:AIA
      WBPaper00061340:AIM
      WBPaper00061340:AIN
      WBPaper00061340:AIY
      WBPaper00061340:ALA
      WBPaper00061340:ALM_BDU
      WBPaper00061340:ALN
      WBPaper00061340:AVA
      WBPaper00061340:AVB
      WBPaper00061340:AVD
      WBPaper00061340:AVE
      WBPaper00061340:AVH
      WBPaper00061340:AVJ
      WBPaper00061340:AVK
      WBPaper00061340:AVL
      WBPaper00061340:CAN
      WBPaper00061340:DA
      WBPaper00061340:DB
      WBPaper00061340:DD
      WBPaper00061340:DVA
      WBPaper00061340:DVC
      WBPaper00061340:FLP
      WBPaper00061340:I5
      WBPaper00061340:ILso
      WBPaper00061340:MC
      WBPaper00061340:Neuroblast_ALM_BDU
      WBPaper00061340:PLM
      WBPaper00061340:PLM_ALN_grandparent
      WBPaper00061340:PVP
      WBPaper00061340:PVT
      WBPaper00061340:RIA
      WBPaper00061340:RID
      WBPaper00061340:RID_parent
      WBPaper00061340:RIH
      WBPaper00061340:RIM
      WBPaper00061340:RIV
      WBPaper00061340:RMD
      WBPaper00061340:RMED
      WBPaper00061340:SIA
      WBPaper00061340:SIB
      WBPaper00061340:SMB
      WBPaper00061340:SMD
      WBPaper00061341:28C_24h_upregulated
      WBPaper00061341:28C_48h_upregulated
      WBPaper00061377:MYRF-1_interacting
      WBPaper00061439:unc-30(ok613)_upregulated
      WBPaper00061479:hda-1(ne4752)_upregulated
      WBPaper00061479:mep-1(ne4629)_upregulated
      WBPaper00061527:R07G3.8_9125-ric-4_17408
      WBPaper00061651:ADA_enriched
      WBPaper00061651:AFD_enriched
      WBPaper00061651:AIZ_enriched
      WBPaper00061651:ASER_enriched
      WBPaper00061651:AUA_enriched
      WBPaper00061651:AWB_enriched
      WBPaper00061651:AWC_OFF_enriched
      WBPaper00061651:AWC_ON_enriched
      WBPaper00061651:BAG_enriched
      WBPaper00061651:DVB_enriched
      WBPaper00061651:DVC_enriched
      WBPaper00061651:FLP_enriched
      WBPaper00061651:RIA_enriched
      WBPaper00061651:RIC_enriched
      WBPaper00061651:RIV_enriched
      WBPaper00061651:RMD_DV_enriched
      WBPaper00061651:RMF_enriched
      WBPaper00061651:SIA_enriched
      WBPaper00061651:SIB_enriched
      WBPaper00061651:URA_enriched
      WBPaper00061651:VB01_enriched
      WBPaper00061651:VC_4_5_enriched
      WBPaper00061651:VC_enriched
      WBPaper00061902:camt-1(ok515)_regulated_URX-AQR-PQR
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062325:muscle_enriched_coding-RNA
      WBPaper00062345:bortezomib_4h_downregulated_N2
      WBPaper00062345:bortezomib_4h_downregulated_zip-1(jy13)
      WBPaper00062456:doxycycline_downregulated_CB4856_protein
      WBPaper00064201:SNA-1_interacting
      WBPaper00064201:SNA-3_interacting
      WBPaper00064306:Agaro-oligosaccharides_upregulated
      WBPaper00064315:mes-3(bn199)_upregulated_EGCs
      WBPaper00064315:mes-4(bn73)_upregulated_EGCs
      WBPaper00064716:paraquat_downregulated
      WBPaper00065029:cadmium_upregulated
      WBPaper00065158:25C_vs_15C_upregulated_AFD
      WBPaper00065158:25C_vs_15C_upregulated_WholeAnimal
      WBPaper00065258:anchor-cell_enriched
      WBPaper00065749:Heat-Shock_upregulated_endu-2(tm4977)
      WBPaper00065749:Heat-Shock_upregulated_N2
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00025032:cluster_52
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026929:Resveratrol_regulated_daf-16
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00029437:dcr-1_upregulated
      WBPaper00030839:Embryo_Pan_Neuronal
      WBPaper00030839:Larval_Pan_Neuronal
      WBPaper00031003:0hr_muscle_depleted
      WBPaper00031003:hlh_1_enriched
      WBPaper00031003:total_muscle_depleted
      WBPaper00031060:2-deoxy-D-glucose_upregulated
      WBPaper00031252:AIN-1_IP_enriched
      WBPaper00031532:Larva_Pan_Neuronal_Enriched
      WBPaper00032165:differentially_expressed_with_age_medoid_1
      WBPaper00035084:L1_enriched_AIN-2_IP
      WBPaper00035084:L2_enriched_AIN-2_IP
      WBPaper00035084:L4_enriched_AIN-2_IP
      WBPaper00035227:heat_shock_regulated
      WBPaper00035588:alg-1(-)_upregulated
      WBPaper00036130:mir-243_up_regulated
      WBPaper00036286:Pattern_I
      WBPaper00037901:GLD-1_mRNA_targets
      WBPaper00040426:CYE-1_CDK-2AF_downregulated
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
      WBPaper00040876:mir-35_downregulated
      WBPaper00040963:Q200_down
      WBPaper00040985:AIN-2_asynchronous_intestine
      WBPaper00040985:AIN-2_asynchronous_muscle
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041960:N2_fasting_upregulated_anytime
      WBPaper00045263:0.1mM-paraquat_downregulated
      WBPaper00045263:isp-1(qm150)_downregulated
      WBPaper00045263:nuo-6(qm200)_downregulated
      WBPaper00045263:ProLongevity-mtROS_downregulated
      WBPaper00045673:colistin_upregulated
      WBPaper00048989:N2_rapamycin_upregulated
      WBPaper00053236:Starvation_regulated_N2
      WBPaper00055899:nitroguanidine_regulated
      [cgc5767]:expression_class_E
      [cgc5767]:expression_class_E_pi(41_min)
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_ME
      [cgc6390]:Cluster_C
    Interaction (210)
  Map_info: Map: V Position: 2.04812 Error: 0.00035
    Positive: Positive_clone: C50F4 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4995
    Pseudo_map_position
  Reference: WBPaper00025088
    WBPaper00038491
    WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene