e1734 : delayed hatching from eggshell rescued by protease or wildtype hatching fluid; QL and descendant cells migrate forward instead of backward. ES1. NA2 (e1907 : same phenotypes).
See also e1734, e1907
[C.elegansII] e1734 : delayed hatching from eggshell rescued by protease or wildtype hatching fluid; QL and descendant cells migrate forward instead of backward. ES1. OA1: e1907 (same phenotypes). [Hedgecock et al. 1987; NJ]
hch-1 encodes a member of the zinc-dependent metalloprotease family that contains an epidermal growth factor-like domain, a CUB domain, and a TSP1 domain and affects hatching and QL neuroblast migration.
Predicted to enable metalloendopeptidase activity. Involved in hatching and neuron migration. Predicted to be located in extracellular region. Expressed in hypodermis and seam cell.