WormBase Tree Display for Gene: WBGene00001749
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| WBGene00001749 | Evidence | Person_evidence | WBPerson1846 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | R107 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | gst-1 | |||||||
| Sequence_name | R107.7 | ||||||||
| Molecular_name | R107.7 | ||||||||
| R107.7.1 | |||||||||
| CE00302 | |||||||||
| Other_name | CE00302 | Paper_evidence | WBPaper00036144 | ||||||
| CELE_R107.7 | Accession_evidence | NDB | BX284603 | ||||||
| Public_name | gst-1 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:25 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | gst | ||||||||
| Allele (13) | |||||||||
| Legacy_information | [C.elegansII] NMK. Encodes predicted glutathione-S-transferase P subunit. Transpliced to SL2. [Weston et al. 1989] | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (18) | |||||||||
| Contained_in_operon | CEOP3572 | ||||||||
| Ortholog (31) | |||||||||
| Paralog (45) | |||||||||
| Structured_description | Concise_description | gst-1 encodes a putative glutathione S-transferase of the pi class;GST-1 is required for sperm to normally migrate towards a PUFA-basedsignal exuded by oocytes; gst-1(RNAi) hermaphrodites are infertile,both through aberrant loss of their own sperm and through failure ofmales to effectively inseminate them. | Paper_evidence | WBPaper00028527 | |||||
| Curator_confirmed | WBPerson48 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 12 Mar 2007 00:00:00 | ||||||||
| Automated_description | Enables glutathione transferase activity. Involved in cellular detoxification; defense response to other organism; and regulation of cellular response to manganese ion. Predicted to be located in cytosol. Expressed in DA neuron. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; autoimmune disease (multiple); carcinoma (multiple); and hematologic cancer (multiple). Is an ortholog of human GSTP1 (glutathione S-transferase pi 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model (137) | ||||||||
| Molecular_info | Corresponding_CDS | R107.7 | |||||||
| Corresponding_transcript | R107.7.1 | ||||||||
| Other_sequence (57) | |||||||||
| Associated_feature | WBsf645457 | ||||||||
| WBsf645458 | |||||||||
| WBsf645459 | |||||||||
| WBsf981541 | |||||||||
| WBsf993558 | |||||||||
| WBsf225512 | |||||||||
| Experimental_info | RNAi_result (11) | ||||||||
| Expr_pattern | Expr11048 | ||||||||
| Expr1018206 | |||||||||
| Expr1031042 | |||||||||
| Expr1155346 | |||||||||
| Expr2012303 | |||||||||
| Expr2030539 | |||||||||
| Drives_construct | WBCnstr00019132 | ||||||||
| WBCnstr00036720 | |||||||||
| Construct_product | WBCnstr00036720 | ||||||||
| Antibody | WBAntibody00002442 | ||||||||
| Microarray_results (22) | |||||||||
| Expression_cluster (205) | |||||||||
| Interaction (46) | |||||||||
| Map_info | Map | III | Position | 0.129472 | Error | 0.002939 | |||
| Positive | Positive_clone | R107 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (23) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
