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WormBase Tree Display for Gene: WBGene00001732

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Name Class

WBGene00001732EvidencePaper_evidenceWBPaper00003717
SMapS_parentSequenceE02A10
IdentityVersion1
NameCGC_namegrl-23Person_evidenceWBPerson83
Sequence_nameE02A10.2
Molecular_name (21)
Other_nameCELE_E02A10.2Accession_evidenceNDBBX284605
Public_namegrl-23
DB_infoDatabaseAceViewgene5N52
WormQTLgeneWBGene00001732
WormFluxgeneWBGene00001732
NDBlocus_tagCELE_E02A10.2
PanthergeneCAEEL|WormBase=WBGene00001732|UniProtKB=Q93424
familyPTHR23261
NCBIgene183983
RefSeqproteinNM_001347275.3
NM_001347272.3
NM_001269502.3
NM_001347276.4
NM_001347271.3
NM_001347273.3
NM_001347274.3
TrEMBLUniProtAccA0A1I6CMA0
Q93424
H2L2E5
A0A1I6CM96
A0A1I6CMA4
A0A1I6CMA3
A0A1I6CM94
UniProt_GCRPUniProtAccQ93424
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:25WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classgrl
Allele (49)
StrainWBStrain00037091
RNASeq_FPKM (74)
Ortholog (22)
Paralog (31)
Structured_descriptionConcise_descriptiongrl-23 encodes a hedgehog-like protein, with (from N- to C-terminus) asignal sequence, a glycine-rich low-complexity region, a Ground-like(Grl) domain, and an acid-rich low-complexity region; the Grl domain ispredicted to form a cysteine-crosslinked protein involved inintercellular signalling, and it has subtle similarity to the N-terminalHedge domain of HEDGEHOG proteins.Paper_evidenceWBPaper00003717
WBPaper00026841
WBPaper00027263
Curator_confirmedWBPerson567
Date_last_updated05 Nov 2006 00:00:00
Automated_descriptionEnriched in AVK; FLP; and neurons based on microarray and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; RNA-seq; and proteomic studies. Is affected by thirteen chemicals including methylmercuric chloride; Tunicamycin; and multi-walled carbon nanotube based on microarray and RNA-seq studies.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSE02A10.2a
E02A10.2b
E02A10.2c
E02A10.2d
E02A10.2e
E02A10.2f
E02A10.2g
Corresponding_CDS_historyE02A10.2b:wp256
Corresponding_transcriptE02A10.2a.1
E02A10.2b.1
E02A10.2c.1
E02A10.2d.1
E02A10.2e.1
E02A10.2f.1
E02A10.2g.1
Other_sequence (188)
Experimental_infoRNAi_resultWBRNAi00043582Inferred_automaticallyRNAi_primary
WBRNAi00030456Inferred_automaticallyRNAi_primary
Expr_patternExpr4425
Expr1028523
Expr1031033
Expr1147571
Expr2012258
Expr2030494
Drives_constructWBCnstr00011987
WBCnstr00036730
Construct_productWBCnstr00036730
Microarray_results (21)
Expression_cluster (109)
Interaction (15)
Map_infoMapVPosition4.51155Error0.002499
PositivePositive_cloneE02A10Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00003717
WBPaper00028754
WBPaper00031588
WBPaper00038491
WBPaper00064105
Remarkground-like gene, contains ground-like domain, hedgehog-relatedPaper_evidenceWBPaper00003717
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene