WormBase Tree Display for Gene: WBGene00001700
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| WBGene00001700 | Evidence | Paper_evidence | WBPaper00003717 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Person_evidence | WBPerson83 | ||||||||
| SMap | S_parent | Sequence | K02E2 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | grd-11 | Person_evidence | WBPerson83 | |||||
| Sequence_name | K02E2.2 | ||||||||
| Molecular_name | K02E2.2 | ||||||||
| K02E2.2.1 | |||||||||
| CE42411 | |||||||||
| Other_name | CELE_K02E2.2 | Accession_evidence | NDB | BX284605 | |||||
| Public_name | grd-11 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:25 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | grd | ||||||||
| Allele (180) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00102132 | ||||||||
| 00109338 | |||||||||
| Ortholog (17) | |||||||||
| Paralog (24) | |||||||||
| Structured_description | Concise_description | grd-11 encodes a hedgehog-like protein, with (from N- to C-terminus) asignal sequence, four Ground domains, an short region of low-complexitysequence, and a Hint/Hog domain; the Hint/Hog domain is predicted to cutGRD-2 into two halves and then covalently link cholesterol to theC-terminus of the Ground domain; the four N-terminal Ground domains arepredicted to form one or more cysteine-crosslinked proteins involved inintercellular signalling; Ground domains have subtle similarity to theN-terminal Hedge domain of HEDGEHOG proteins; grd-11 has no obviousfunction in RNAi assays. | Paper_evidence | WBPaper00003717 | |||||
| WBPaper00026841 | |||||||||
| WBPaper00027263 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 05 Nov 2006 00:00:00 | ||||||||
| Automated_description | Predicted to be involved in protein autoprocessing. Predicted to be located in extracellular region. Human ortholog(s) of this gene implicated in several diseases, including bone disease (multiple); gastrointestinal system cancer (multiple); and glomerulonephritis (multiple). Is an ortholog of human DHH (desert hedgehog signaling molecule); IHH (Indian hedgehog signaling molecule); and SHH (sonic hedgehog signaling molecule). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model (30) | ||||||||
| Molecular_info | Corresponding_CDS | K02E2.2 | |||||||
| Corresponding_CDS_history | K02E2.2:wp188 | ||||||||
| Corresponding_transcript | K02E2.2.1 | ||||||||
| Associated_feature (17) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00049719 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00016465 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00033872 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00077000 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr4421 | ||||||||
| Expr1014393 | |||||||||
| Expr1031015 | |||||||||
| Expr1153441 | |||||||||
| Expr2012225 | |||||||||
| Expr2030461 | |||||||||
| Drives_construct | WBCnstr00011983 | ||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (127) | |||||||||
| Interaction (448) | |||||||||
| WBProcess | WBbiopr:00000123 | ||||||||
| Map_info | Map | V | Position | 24.9876 | Error | 0.000485 | |||
| Positive | Positive_clone | K02E2 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00003717 | ||||||||
| WBPaper00026841 | |||||||||
| WBPaper00028754 | |||||||||
| WBPaper00031588 | |||||||||
| WBPaper00059191 | |||||||||
| WBPaper00064105 | |||||||||
| Remark | Contains 4repeats of the Ground domain and one Hog domain | Paper_evidence | WBPaper00003717 | ||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
