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WormBase Tree Display for Gene: WBGene00001685

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Name Class

WBGene00001685SMapS_parentSequenceK10B3
IdentityVersion1
NameCGC_namegpd-3Person_evidenceWBPerson1051
Sequence_nameK10B3.7
Molecular_nameK10B3.7
K10B3.7.1
CE07370
Other_nameCELE_K10B3.7Accession_evidenceNDBBX284606
Public_namegpd-3
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:25WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classgpd
Allele (25)
Legacy_information[C.elegansII] Deleted in Bergerac strains; no apparent phenotype. Encodes glyceraldehyde-3-phosphate-dehydrogenase, major muscle-specific isozyme(GAPDHase-2), expression increases postembryonically. Final gene in operon with mai-1, gpd-2. [Barrios et al. 1989; Spieth et al. 1993; HH; BL]
StrainWBStrain00037109
RNASeq_FPKM (74)
GO_annotation (14)
Contained_in_operonCEOPX036
Ortholog (54)
ParalogWBGene00001683Caenorhabditis elegansFrom_analysisInparanoid_8
Panther
WormBase-Compara
WBGene00001684Caenorhabditis elegansFrom_analysisInparanoid_8
Panther
WormBase-Compara
WBGene00001686Caenorhabditis elegansFrom_analysisTreeFam
Inparanoid_8
Panther
WormBase-Compara
Structured_descriptionConcise_descriptiongpd-3 encodes a predicted glyceraldehyde 3-phosphate dehydrogenase that affects embryonic viability; GPD-3 interacts with LIN-2 in two-hybrid assays.Paper_evidenceWBPaper00003839
WBPaper00004651
Curator_confirmedWBPerson48
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity. Predicted to be involved in glycolytic process. Predicted to be located in cytosol. Expressed in several structures, including gonad; intestine; and pharynx. Human ortholog(s) of this gene implicated in Alzheimer's disease and lymphangioleiomyomatosis. Is an ortholog of human GAPDH (glyceraldehyde-3-phosphate dehydrogenase).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:10652Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:4141)
DOID:3319Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:4141)
Molecular_infoCorresponding_CDSK10B3.7
Corresponding_transcriptK10B3.7.1
Other_sequence (55)
Associated_featureWBsf653809
WBsf670282
WBsf978989
WBsf982141
WBsf237143
WBsf237144
Experimental_infoRNAi_result (19)
Expr_patternExpr779
Expr4044
Expr12932
Expr13108
Expr15766
Expr1010311
Expr1031005
Expr1154190
Expr2012207
Expr2030443
Drives_constructWBCnstr00021140
WBCnstr00036771
WBCnstr00042513
Construct_product (2)
Microarray_results (32)
Expression_cluster (246)
Interaction (135)
Map_infoMapXPosition-12.1532Error0.007375
PositivePositive_cloneHH#L16B
K10B3Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (53)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene