WormBase Tree Display for Gene: WBGene00001678
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WBGene00001678 | SMap | S_parent | Sequence | Y95B8A | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 1 | |||||||
Name | CGC_name | gpa-16 | Person_evidence | WBPerson625 | |||||
Sequence_name | Y95B8A.5 | ||||||||
Molecular_name | Y95B8A.5a | ||||||||
Y95B8A.5a.1 | |||||||||
CE24692 | |||||||||
Y95B8A.5b | |||||||||
CE49289 | |||||||||
Y95B8A.5c | |||||||||
CE49147 | |||||||||
Y95B8A.5b.1 | |||||||||
Y95B8A.5c.1 | |||||||||
Other_name | spn-1 | CGC_data_submission | |||||||
CELE_Y95B8A.5 | Accession_evidence | NDB | BX284601 | ||||||
Public_name | gpa-16 | ||||||||
DB_info | Database (11) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:25 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | gpa | ||||||||
Allele (171) | |||||||||
Legacy_information | [Rose LS, Bergmann DC] spn for spindle orientation defective. it143 is a temperature- sensitive maternal effect allele. Embryos from homozygous mutant mothers misorient early cleavage planes at 20C and 25C. A significant percentage of adult escapers show reversal of organ situs. | ||||||||
Strain | WBStrain00028999 | ||||||||
WBStrain00032507 | |||||||||
WBStrain00003996 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (28) | |||||||||
Ortholog (94) | |||||||||
Paralog (22) | |||||||||
Structured_description | Concise_description | gpa-16 encodes a G protein alpha subunit; gpa-16 is required for spindle position and orientation in embryos; gpa-16 is expressed in AVM, PDE, PLM, BDU, PVC, and RIP, and weakly expressed in the pharynx, body-wall muscle, and vulval muscle. | Curator_confirmed | WBPerson48 | |||||
WBPerson567 | |||||||||
Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
Automated_description | Predicted to enable several functions, including G-protein beta/gamma-subunit complex binding activity; GTPase activity; and guanyl ribonucleotide binding activity. Involved in embryonic axis specification and establishment of mitotic spindle orientation. Located in cell cortex. Expressed in several structures, including Psub4; Z2; Z3; neurons; and pharynx. Human ortholog(s) of this gene implicated in achromatopsia 4; congenital stationary night blindness 1G; and congenital stationary night blindness autosomal dominant 3. Is an ortholog of human GNAI1 (G protein subunit alpha i1). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model | DOID:0110714 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4393) | ||||
DOID:13399 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4394) | ||||||
DOID:0110715 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4393) | ||||||
DOID:0110010 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4394) | ||||||
DOID:8499 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4393) | ||||||
EFO:MONDO:0000107 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4387) | ||||||
Molecular_info | Corresponding_CDS | Y95B8A.5a | |||||||
Y95B8A.5b | |||||||||
Y95B8A.5c | |||||||||
Corresponding_transcript | Y95B8A.5a.1 | ||||||||
Y95B8A.5b.1 | |||||||||
Y95B8A.5c.1 | |||||||||
Other_sequence (21) | |||||||||
Associated_feature | WBsf655875 | ||||||||
WBsf982618 | |||||||||
WBsf1009159 | |||||||||
Experimental_info | RNAi_result (18) | ||||||||
Expr_pattern | Expr1316 | ||||||||
Expr2575 | |||||||||
Expr3781 | |||||||||
Expr12571 | |||||||||
Expr15821 | |||||||||
Expr1023029 | |||||||||
Expr1030999 | |||||||||
Expr1162089 | |||||||||
Expr2012187 | |||||||||
Expr2030423 | |||||||||
Drives_construct | WBCnstr00020759 | ||||||||
WBCnstr00021620 | |||||||||
WBCnstr00036778 | |||||||||
WBCnstr00042538 | |||||||||
Construct_product | WBCnstr00010213 | ||||||||
WBCnstr00036778 | |||||||||
Antibody | WBAntibody00000943 | ||||||||
Microarray_results (19) | |||||||||
Expression_cluster (119) | |||||||||
Interaction (109) | |||||||||
WBProcess | WBbiopr:00000017 | ||||||||
Map_info | Map | I | Position | -17.8143 | Error | 0.029039 | |||
Positive | Positive_clone | Y95B8A | Inferred_automatically | From CDS info | |||||
From sequence, transcript, pseudogene data | |||||||||
Mapping_data | 2_point | 7070 | |||||||
Reference (72) | |||||||||
Remark | main name / other name relation between these two loci has been swapped. Main name (gpa-1) = other name (spn-1) assignment was updated on August, 2003 | CGC_data_submission | |||||||
spn-1 has been mistakenly referred to as srp-7 [021127 ck1] | Paper_evidence | WBPaper00005351 | |||||||
Method | Gene |