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WormBase Tree Display for Gene: WBGene00001666

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Name Class

WBGene00001666SMapS_parentSequenceT07A9
IdentityVersion1
NameCGC_namegpa-4Person_evidenceWBPerson625
Sequence_nameT07A9.7
Molecular_nameT07A9.7
T07A9.7.1
CE31599
Other_nameCELE_T07A9.7Accession_evidenceNDBBX284604
Public_namegpa-4
DB_infoDatabaseAceViewgene4B157
WormQTLgeneWBGene00001666
WormFluxgeneWBGene00001666
NDBlocus_tagCELE_T07A9.7
PanthergeneCAEEL|WormBase=WBGene00001666|UniProtKB=Q9BIG5
familyPTHR10218
NCBIgene176865
RefSeqproteinNM_067520.9
SwissProtUniProtAccQ9BIG5
UniProt_GCRPUniProtAccQ9BIG5
OMIMgene139330
139340
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:25WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classgpa
Allele (75)
StrainWBStrain00024184
WBStrain00024185
WBStrain00028935
RNASeq_FPKM (74)
GO_annotation (18)
Contained_in_operonCEOP4020
Ortholog (78)
Paralog (21)
Structured_descriptionConcise_descriptiongpa-4 encodes a member of the G protein alpha subunit family of heterotrimeric GTPases; it is expressed in ASI.Curator_confirmedWBPerson48
WBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable G protein-coupled receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Predicted to be involved in adenylate cyclase-modulating G protein-coupled receptor signaling pathway. Located in non-motile cilium. Expressed in several structures, including P lineage cell; body wall musculature; neurons; somatic gonad; and vulval precursor cell. Human ortholog(s) of this gene implicated in achromatopsia 4; congenital stationary night blindness 1G; and congenital stationary night blindness autosomal dominant 3. Is an ortholog of human GNAI1 (G protein subunit alpha i1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0110714Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:4393)
DOID:13399Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:4394)
DOID:0110715Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:4393)
DOID:0110010Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:4394)
DOID:8499Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:4393)
Molecular_infoCorresponding_CDST07A9.7
Corresponding_CDS_historyT07A9.7:wp82
Corresponding_transcriptT07A9.7.1
Other_sequenceDviv_isotig21697
MA01440
JI459694.1
FG581161.1
ES743786.1
HBC18245_1
FG350092.1
MIC06760_1
MAC00743_1
Associated_featureWBsf659817
WBsf659876
WBsf227841
Experimental_infoRNAi_resultWBRNAi00094896Inferred_automaticallyRNAi_primary
WBRNAi00035287Inferred_automaticallyRNAi_primary
WBRNAi00052707Inferred_automaticallyRNAi_primary
WBRNAi00018334Inferred_automaticallyRNAi_primary
Expr_patternExpr1305
Expr15538
Expr1020605
Expr1156317
Expr2012193
Expr2030429
Drives_construct (23)
Construct_productWBCnstr00001686
WBCnstr00010201
WBCnstr00036790
Microarray_results (19)
Expression_cluster (96)
Interaction (45)
Map_infoMapIVPosition-26.2029Error0.019408
PositivePositive_cloneT07A9Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point4370
4454
4691
Pseudo_map_position
Reference (19)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene