WormBase Tree Display for Gene: WBGene00001591
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| WBGene00001591 | SMap | S_parent | Sequence | F11A5 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | glc-1 | Person_evidence | WBPerson32 | |||||
| Sequence_name | F11A5.10 | ||||||||
| Molecular_name | F11A5.10 | ||||||||
| F11A5.10.1 | |||||||||
| CE24896 | |||||||||
| Other_name | GluCl alpha | Paper_evidence | WBPaper00005494 | ||||||
| WBPaper00044702 | |||||||||
| CELE_F11A5.10 | Accession_evidence | NDB | BX284605 | ||||||
| Public_name | glc-1 | ||||||||
| DB_info | Database | AceView | gene | 5Q701 | |||||
| WormQTL | gene | WBGene00001591 | |||||||
| WormFlux | gene | WBGene00001591 | |||||||
| NDB | locus_tag | CELE_F11A5.10 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00001591|UniProtKB=G5EBR3 | |||||||
| family | PTHR18945 | ||||||||
| NCBI | gene | 180086 | |||||||
| RefSeq | protein | NM_074689.7 | |||||||
| SwissProt | UniProtAcc | G5EBR3 | |||||||
| UniProt_GCRP | UniProtAcc | G5EBR3 | |||||||
| OMIM | gene | 138491 | |||||||
| 138492 | |||||||||
| 305990 | |||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:25 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | glc | ||||||||
| Allele | WBVar01592780 | ||||||||
| WBVar00033205 | |||||||||
| WBVar01592781 | |||||||||
| WBVar01592782 | |||||||||
| WBVar01592783 | |||||||||
| WBVar00033210 | |||||||||
| WBVar01592784 | |||||||||
| WBVar01592785 | |||||||||
| WBVar00033215 | |||||||||
| WBVar01592786 | |||||||||
| WBVar01592787 | |||||||||
| WBVar01592788 | |||||||||
| WBVar01592789 | |||||||||
| WBVar00033220 | |||||||||
| WBVar01592790 | |||||||||
| WBVar00033225 | |||||||||
| WBVar00033230 | |||||||||
| WBVar00033235 | |||||||||
| WBVar00033240 | |||||||||
| WBVar02153671 | |||||||||
| WBVar01746008 | |||||||||
| WBVar01746009 | |||||||||
| WBVar01746010 | |||||||||
| WBVar01746011 | |||||||||
| WBVar00239197 | |||||||||
| WBVar02050087 | |||||||||
| WBVar02122682 | |||||||||
| WBVar02104839 | |||||||||
| WBVar02104840 | |||||||||
| WBVar02104841 | |||||||||
| WBVar01905387 | |||||||||
| WBVar01905388 | |||||||||
| WBVar01905389 | |||||||||
| WBVar01901140 | |||||||||
| WBVar01078893 | |||||||||
| WBVar01078894 | |||||||||
| WBVar00593197 | |||||||||
| WBVar01078895 | |||||||||
| WBVar00593198 | |||||||||
| WBVar01078896 | |||||||||
| WBVar00593200 | |||||||||
| WBVar01078897 | |||||||||
| WBVar00593203 | |||||||||
| WBVar00593204 | |||||||||
| WBVar01078898 | |||||||||
| WBVar00593205 | |||||||||
| WBVar01078899 | |||||||||
| WBVar00480831 | |||||||||
| WBVar01078900 | |||||||||
| WBVar00593206 | |||||||||
| WBVar01078901 | |||||||||
| WBVar00593210 | |||||||||
| WBVar00480832 | |||||||||
| WBVar01078902 | |||||||||
| WBVar00593211 | |||||||||
| WBVar00480833 | |||||||||
| WBVar01078903 | |||||||||
| WBVar00593212 | |||||||||
| WBVar01078904 | |||||||||
| WBVar00593213 | |||||||||
| WBVar00593214 | |||||||||
| WBVar01078905 | |||||||||
| WBVar01078906 | |||||||||
| WBVar00593216 | |||||||||
| WBVar01078907 | |||||||||
| WBVar02148333 | |||||||||
| WBVar01078908 | |||||||||
| WBVar02121633 | |||||||||
| WBVar01809317 | |||||||||
| WBVar02123301 | |||||||||
| WBVar01498548 | |||||||||
| WBVar02121289 | |||||||||
| WBVar02024991 | |||||||||
| WBVar02124057 | |||||||||
| WBVar00033145 | |||||||||
| WBVar01633577 | |||||||||
| WBVar01499299 | |||||||||
| WBVar01633578 | |||||||||
| WBVar00033150 | |||||||||
| WBVar01633579 | |||||||||
| WBVar00254646 | |||||||||
| WBVar01633580 | |||||||||
| WBVar00033155 | |||||||||
| WBVar01633581 | |||||||||
| WBVar01633582 | |||||||||
| WBVar00033160 | |||||||||
| WBVar00033165 | |||||||||
| WBVar02123706 | |||||||||
| WBVar00033170 | |||||||||
| WBVar02124626 | |||||||||
| WBVar02094631 | |||||||||
| WBVar01592761 | |||||||||
| WBVar02124261 | |||||||||
| WBVar00033175 | |||||||||
| WBVar01592762 | |||||||||
| WBVar01991198 | |||||||||
| WBVar01592763 | |||||||||
| WBVar01592764 | |||||||||
| WBVar01592765 | |||||||||
| WBVar00033180 | |||||||||
| WBVar01592766 | |||||||||
| WBVar01592767 | |||||||||
| WBVar00033185 | |||||||||
| WBVar01592768 | |||||||||
| WBVar01777621 | |||||||||
| WBVar01592769 | |||||||||
| WBVar01592770 | |||||||||
| WBVar01777622 | |||||||||
| WBVar00033190 | |||||||||
| WBVar01592771 | |||||||||
| WBVar01592772 | |||||||||
| WBVar01592773 | |||||||||
| WBVar01592774 | |||||||||
| WBVar00033195 | |||||||||
| WBVar01592775 | |||||||||
| WBVar01592776 | |||||||||
| WBVar00033200 | |||||||||
| WBVar01592777 | |||||||||
| WBVar01592778 | |||||||||
| WBVar02124830 | |||||||||
| WBVar01592779 | |||||||||
| Strain (12) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (32) | |||||||||
| Ortholog (38) | |||||||||
| Paralog (101) | |||||||||
| Structured_description | Concise_description | glc-1 encodes the alpha subunit of a glutamate-gated chloride channel and forms a functional channel in Xenopus oocytes; mutations genetically interact with avr-14 and avr-15 mutations such that triple mutants exhibit high level resistance to ivermectin. | Paper_evidence | WBPaper00002049 | |||||
| WBPaper00003319 | |||||||||
| WBPaper00003954 | |||||||||
| Curator_confirmed | WBPerson48 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Enables extracellularly glutamate-gated chloride channel activity; glutamate binding activity; and identical protein binding activity. Involved in chloride transmembrane transport; locomotion involved in locomotory behavior; and protein complex oligomerization. Located in plasma membrane. Expressed in body wall musculature; head neurons; and pharyngeal muscle cell. Human ortholog(s) of this gene implicated in hyperekplexia 1; hyperekplexia 2; and syndromic X-linked intellectual disability Pilorge type. Is an ortholog of human GLRA2 (glycine receptor alpha 2) and GLRA3 (glycine receptor alpha 3). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0070422 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4327) | ||||
| DOID:0060696 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4326) | ||||||
| DOID:0060697 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4329) | ||||||
| Molecular_info | Corresponding_CDS | F11A5.10 | |||||||
| Corresponding_transcript | F11A5.10.1 | ||||||||
| Other_sequence (15) | |||||||||
| Associated_feature | WBsf647623 | ||||||||
| WBsf233084 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00044346 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00103267 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00085188 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00103268 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00030804 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00066347 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00085186 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00085187 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00013102 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00085184 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr9953 | ||||||||
| Expr1021950 | |||||||||
| Expr1148282 | |||||||||
| Expr2012079 | |||||||||
| Expr2030315 | |||||||||
| Drives_construct | WBCnstr00009990 | ||||||||
| WBCnstr00009991 | |||||||||
| WBCnstr00009992 | |||||||||
| WBCnstr00009993 | |||||||||
| WBCnstr00009994 | |||||||||
| WBCnstr00009995 | |||||||||
| WBCnstr00009996 | |||||||||
| WBCnstr00014965 | |||||||||
| WBCnstr00036841 | |||||||||
| Construct_product | WBCnstr00009990 | ||||||||
| WBCnstr00009991 | |||||||||
| WBCnstr00009992 | |||||||||
| WBCnstr00009993 | |||||||||
| WBCnstr00009994 | |||||||||
| WBCnstr00009995 | |||||||||
| WBCnstr00009996 | |||||||||
| WBCnstr00014965 | |||||||||
| WBCnstr00036841 | |||||||||
| Microarray_results (20) | |||||||||
| Expression_cluster (239) | |||||||||
| Interaction (73) | |||||||||
| Map_info | Map | V | Position | 9.84523 | Error | 0.001681 | |||
| Positive | Positive_clone | F11A5 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (32) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
