WormBase Tree Display for Gene: WBGene00001425
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| WBGene00001425 | Evidence | Person_evidence | WBPerson117 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | F13B9 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | fis-2 | Person_evidence | WBPerson117 | |||||
| Sequence_name | F13B9.8 | ||||||||
| Molecular_name | F13B9.8 | ||||||||
| F13B9.8.1 | |||||||||
| CE37102 | |||||||||
| Other_name | CELE_F13B9.8 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | fis-2 | ||||||||
| DB_info | Database | AceView | gene | XI900 | |||||
| WormQTL | gene | WBGene00001425 | |||||||
| WormFlux | gene | WBGene00001425 | |||||||
| NDB | locus_tag | CELE_F13B9.8 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00001425|UniProtKB=Q6AHP8 | |||||||
| family | PTHR13247 | ||||||||
| NCBI | gene | 184409 | |||||||
| RefSeq | protein | NM_001029389.7 | |||||||
| SwissProt | UniProtAcc | Q6AHP8 | |||||||
| UniProt_GCRP | UniProtAcc | Q6AHP8 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:24 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | fis | ||||||||
| Allele (32) | |||||||||
| Strain | WBStrain00036081 | ||||||||
| WBStrain00036105 | |||||||||
| WBStrain00036310 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (15) | |||||||||
| Ortholog (34) | |||||||||
| Paralog | WBGene00001424 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | fis-2 encodes a protein similar to the yeast and human Fis1 proteins involved in mitochondrial fission; fis-2 functions downstream of, or in parallel to, the ced-3 caspase during apoptosis and does not seem to be required for mitochondrial fission but it is possible that it may function redundantly along with fis-1 and other genes; the fis-2 protein localizes to mitochondria. | Paper_evidence | WBPaper00032123 | |||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 22 Oct 2010 00:00:00 | ||||||||
| Automated_description | Involved in apoptotic process. Acts upstream of or within IRE1-mediated unfolded protein response. Located in mitochondrion. Human ortholog(s) of this gene implicated in Alzheimer's disease. Is an ortholog of human FIS1 (fission, mitochondrial 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:10652 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:21689) | ||||
| Molecular_info | Corresponding_CDS | F13B9.8 | |||||||
| Corresponding_CDS_history | F13B9.8:wp128 | ||||||||
| F13B9.8a:wp271 | |||||||||
| Corresponding_transcript | F13B9.8.1 | ||||||||
| Other_sequence | CJC04355_1 | ||||||||
| CBC11363_1 | |||||||||
| Associated_feature | WBsf670828 | ||||||||
| WBsf1006101 | |||||||||
| WBsf1006102 | |||||||||
| WBsf237667 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00030875 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00044489 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00114732 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00114731 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00013201 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00114730 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1016157 | ||||||||
| Expr1030850 | |||||||||
| Expr1148438 | |||||||||
| Expr2011793 | |||||||||
| Expr2030031 | |||||||||
| Drives_construct | WBCnstr00036959 | ||||||||
| Construct_product | WBCnstr00009308 | ||||||||
| WBCnstr00009309 | |||||||||
| WBCnstr00036959 | |||||||||
| Microarray_results (23) | |||||||||
| Expression_cluster (147) | |||||||||
| Interaction | WBInteraction000135884 | ||||||||
| WBInteraction000232353 | |||||||||
| WBInteraction000285065 | |||||||||
| WBInteraction000323665 | |||||||||
| WBInteraction000391317 | |||||||||
| WBInteraction000416344 | |||||||||
| WBInteraction000432886 | |||||||||
| WBInteraction000463041 | |||||||||
| Map_info | Map | X | Position | -0.194898 | Error | 0.00328 | |||
| Positive | Positive_clone | F13B9 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 5153 | |||||||
| 4200 | |||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00032123 | ||||||||
| WBPaper00038491 | |||||||||
| WBPaper00044205 | |||||||||
| WBPaper00045775 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00055144 | |||||||||
| WBPaper00059545 | |||||||||
| WBPaper00059627 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
