WormBase Tree Display for Gene: WBGene00001410
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| WBGene00001410 | SMap | S_parent | Sequence | Y54F10AM | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | feh-1 | Person_evidence | WBPerson52 | |||||
| Sequence_name | Y54F10AM.2 | ||||||||
| Molecular_name (14) | |||||||||
| Other_name | CELE_Y54F10AM.2 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | feh-1 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:24 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | feh | ||||||||
| Allele (248) | |||||||||
| Strain | WBStrain00003277 | ||||||||
| WBStrain00028627 | |||||||||
| WBStrain00028628 | |||||||||
| WBStrain00032616 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (14) | |||||||||
| Ortholog (39) | |||||||||
| Structured_description | Concise_description | feh-1 encodes the single C. elegans member of the Fe65 protein family that affects embryonic and larval viability and pharyngeal pumping; the PTB2 domain binds to cytosolic domain of C. elegans APL-1 in vitro; expressed in the neuromuscular structures of the pharynx and in a subset of neurons. | Paper_evidence | WBPaper00005169 | |||||
| Curator_confirmed | WBPerson48 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Enables amyloid-beta binding activity. Involved in embryo development; feeding behavior; and nematode larval development. Located in actin filament. Expressed in nerve ring; pharynx; tail neurons; and ventral cord neurons. Human ortholog(s) of this gene implicated in Alzheimer's disease and cognitive disorder. Is an ortholog of human APBB2 (amyloid beta precursor protein binding family B member 2). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:10652 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:581,HGNC:582) | ||||
| DOID:1561 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:582) | ||||||
| Molecular_info | Corresponding_CDS | Y54F10AM.2a | |||||||
| Y54F10AM.2b | |||||||||
| Y54F10AM.2c | |||||||||
| Y54F10AM.2d | |||||||||
| Corresponding_CDS_history | Y54F10AM.2c:wp143 | ||||||||
| Corresponding_transcript | Y54F10AM.2a.1 | ||||||||
| Y54F10AM.2b.1 | |||||||||
| Y54F10AM.2c.1 | |||||||||
| Y54F10AM.2c.2 | |||||||||
| Y54F10AM.2d.1 | |||||||||
| Y54F10AM.2d.2 | |||||||||
| Other_sequence (57) | |||||||||
| Associated_feature (21) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00057399 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00063449 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00063448 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Chronogram110 | ||||||||
| Expr1865 | |||||||||
| Expr1866 | |||||||||
| Expr1020162 | |||||||||
| Expr1030844 | |||||||||
| Expr1160831 | |||||||||
| Expr2011748 | |||||||||
| Expr2029986 | |||||||||
| Drives_construct | WBCnstr00003748 | ||||||||
| WBCnstr00010495 | |||||||||
| Construct_product | WBCnstr00010495 | ||||||||
| Regulate_expr_cluster | WBPaper00031674:feh-1(gb561)(RNAi)_downregulated | ||||||||
| WBPaper00031674:feh-1(gb561)(RNAi)_upregulated | |||||||||
| Antibody | WBAntibody00000474 | ||||||||
| Microarray_results (27) | |||||||||
| Expression_cluster (224) | |||||||||
| Interaction (23) | |||||||||
| Map_info | Map | III | Position | -12.3627 | Error | 0.181296 | |||
| Positive | Positive_clone | Y54F10AM | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 4306 | |||||||
| 4853 | |||||||||
| 4820 | |||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00005169 | ||||||||
| WBPaper00011375 | |||||||||
| WBPaper00024452 | |||||||||
| WBPaper00031506 | |||||||||
| WBPaper00031674 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00039323 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00064648 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
