WormBase Tree Display for Gene: WBGene00001037
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WBGene00001037 | SMap | S_parent | Sequence | T05C3 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||||
Name | CGC_name | dnj-19 | Person_evidence | WBPerson625 | |||||
Sequence_name | T05C3.5 | ||||||||
Molecular_name | T05C3.5 | ||||||||
T05C3.5.1 | |||||||||
CE13229 | |||||||||
Other_name | dnj-6 | Person_evidence | WBPerson625 | ||||||
CELE_T05C3.5 | Accession_evidence | NDB | BX284605 | ||||||
Public_name | dnj-19 | ||||||||
DB_info | Database | AceView | gene | 5F982 | |||||
WormQTL | gene | WBGene00001037 | |||||||
WormFlux | gene | WBGene00001037 | |||||||
NDB | locus_tag | CELE_T05C3.5 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00001037|UniProtKB=O16303 | |||||||
family | PTHR43888 | ||||||||
NCBI | gene | 3565862 | |||||||
RefSeq | protein | NM_072051.8 | |||||||
TrEMBL | UniProtAcc | O16303 | |||||||
UniProt_GCRP | UniProtAcc | O16303 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:22 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
2 | 16 Dec 2005 10:14:29 | WBPerson1849 | Event | Acquires_merge | WBGene00001024 | ||||
Name_change | Other_name | dnj-6 | |||||||
Acquires_merge | WBGene00001024 | ||||||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | dnj | ||||||||
Allele (36) | |||||||||
Strain | WBStrain00036527 | ||||||||
WBStrain00036534 | |||||||||
WBStrain00036688 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (11) | |||||||||
Ortholog (38) | |||||||||
Paralog | WBGene00001030 | Caenorhabditis elegans | From_analysis | Panther | |||||
WormBase-Compara | |||||||||
WBGene00001028 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
WBGene00001036 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
Structured_description | Concise_description | This gene encodes a protein containing a DnaJ ('J') domain. | Paper_evidence | WBPaper00012768 | |||||
WBPaper00012859 | |||||||||
Curator_confirmed | WBPerson567 | ||||||||
Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
Automated_description | Predicted to enable protein-folding chaperone binding activity. Involved in response to topologically incorrect protein. Predicted to be located in cytosol. Is an ortholog of human DNAJA2 (DnaJ heat shock protein family (Hsp40) member A2). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Disease_relevance | C. elegans is an effective model system to study heat-related pathologies like heat stroke; in elegans, the heat-shock transcription factor, after activation, induces the expression of other small heat shock proteins (sHSP); HSP-16.1 has a protective effect against heat-induced necrosis; HSP-16.1 localizes to the golgi and functions together with the PMR-1/PMR1 Ca2+ and Mn2+ transporting ATPase, and NUCB-1/Nucleobindin1, a golgi-located calcium-buffering protein, to maintain calcium homeostasis, under heat stroke; overexpresiion of pmr-1/PMR1 is sufficient to promote survival after heat stroke, bypassing both HSF-1 and HSP-16.1, indicating that PMR-1/PMR1 functions downstream of both these genes; also, the sHSPs, HSP-16.1, HSP-16.41 and DNJ-19 are required for an acquired tolerance to heat stroke. | Homo sapiens | Paper_evidence | WBPaper00041564 | ||||
Curator_confirmed | WBPerson324 | ||||||||
Date_last_updated | 29 May 2013 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | T05C3.5 | |||||||
Corresponding_transcript | T05C3.5.1 | ||||||||
Other_sequence (74) | |||||||||
Associated_feature (3) | |||||||||
Experimental_info | RNAi_result | WBRNAi00035196 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00063654 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00018224 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00052501 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00011119 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00106334 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00041102 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00081619 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00076648 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Expr1021572 | ||||||||
Expr1030649 | |||||||||
Expr1156125 | |||||||||
Expr2010993 | |||||||||
Expr2029231 | |||||||||
Drives_construct | WBCnstr00037126 | ||||||||
WBCnstr00039336 | |||||||||
Construct_product | WBCnstr00037126 | ||||||||
WBCnstr00039336 | |||||||||
Antibody | WBAntibody00002787 | ||||||||
WBAntibody00002797 | |||||||||
Microarray_results (28) | |||||||||
Expression_cluster (120) | |||||||||
Interaction (309) | |||||||||
Map_info | Map | V | Position | -1.79099 | Error | 0.011606 | |||
Positive | Positive_clone | T05C3 | Inferred_automatically | From CDS info | |||||
From sequence, transcript, pseudogene data | |||||||||
Pseudo_map_position | |||||||||
Reference | WBPaper00006377 | ||||||||
WBPaper00031384 | |||||||||
WBPaper00034765 | |||||||||
WBPaper00038491 | |||||||||
WBPaper00055090 | |||||||||
WBPaper00061655 | |||||||||
WBPaper00064733 | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |