WormBase Tree Display for Gene: WBGene00000966

WBGene00000966 SMap: S_parent: Sequence: F55A12
  Identity: Version: 1
    Name: CGC_name: dhs-2 Person_evidence: WBPerson651
      Sequence_name: F55A12.4
      Molecular_name: F55A12.4a
        F55A12.4a.1
        CE26924
        F55A12.4b
        CE51265
        F55A12.4c
        CE11123
        F55A12.4b.1
        F55A12.4c.1
      Other_name: CELE_F55A12.4 Accession_evidence: NDB BX284601
      Public_name: dhs-2
    DB_info: Database: AceView gene 1F923
        WormQTL gene WBGene00000966
        WormFlux gene WBGene00000966
        NDB locus_tag CELE_F55A12.4
        Panther gene CAEEL|WormBase=WBGene00000966|UniProtKB=O01758
          family PTHR43313
        NCBI gene 172183
        RefSeq protein NM_001392303.1
            NM_059174.9
            NM_001322672.3
        TrEMBL UniProtAcc H2KYZ9
            O01758
            Q86NJ7
        UniProt_GCRP UniProtAcc O01758
        OMIM gene 601617
            609769
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:22 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: dhs
    Allele (41)
    RNASeq_FPKM (74)
    GO_annotation: 00022005
      00022006
      00022007
      00022008
      00025475
    Ortholog: WBGene00060045 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00033287 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00147635 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00117413 Pristionchus pacificus From_analysis: OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00124204 Caenorhabditis japonica From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00108441 Pristionchus pacificus From_analysis: Inparanoid_8
            WormBase-Compara
      WBGene00111699 Pristionchus pacificus From_analysis: Inparanoid_8
            WormBase-Compara
      WBGene00111677 Pristionchus pacificus From_analysis: Inparanoid_8
            WormBase-Compara
      CBOVI.g10337 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g8021 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g10188 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g1761 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g2345 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g8244 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g4803 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g13330 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g9896 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g24284 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00323.g9202 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cang_2012_03_13_00323.g9203 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cang_2012_03_13_13414.g24218 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cni-dhs-2 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold630.g20499 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00314.g9253 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_07114 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_002572 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g06055 Oscheius tipulae From_analysis: WormBase-Compara
      Sp34_10244800 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrI_pilon.g897 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00111689 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00280134 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00291758 Trichuris muris From_analysis: WormBase-Compara
      WBGene00296581 Trichuris muris From_analysis: WormBase-Compara
      WBGene00301657 Trichuris muris From_analysis: WormBase-Compara
      FB:FBgn0033679 Drosophila melanogaster From_analysis: Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      ZFIN:ZDB-GENE-030131-1249 Danio rerio From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-030912-15 Danio rerio From_analysis: Hieranoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:9940 Homo sapiens From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:29674 Homo sapiens From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:23316 Homo sapiens From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:16888 Homo sapiens From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:29958 Homo sapiens From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:1351670 Mus musculus From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
      MGI:2442798 Mus musculus From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
      RGD:620655 Rattus norvegicus From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
      RGD:708343 Rattus norvegicus From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
    Paralog (38)
    Structured_description: Concise_description: dhs-2 encodes a short-chain dehydrogenase predicted to be mitochondrial. Paper_evidence: WBPaper00004424
          Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable oxidoreductase activity. Predicted to be involved in steroid metabolic process. Predicted to be located in intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis 13; fundus albipunctatus; and night blindness. Is an ortholog of several human genes including HSD17B6 (hydroxysteroid 17-beta dehydrogenase 6); RDH16 (retinol dehydrogenase 16); and RDH5 (retinol dehydrogenase 5). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0080257 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:29958)
      DOID:11105 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:9940)
      DOID:8499 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:9940)
  Molecular_info: Corresponding_CDS: F55A12.4a
      F55A12.4b
      F55A12.4c
    Corresponding_CDS_history: F55A12.4b:wp252
    Corresponding_transcript: F55A12.4a.1
      F55A12.4b.1
      F55A12.4c.1
    Other_sequence: CRC07315_1
      CJC05535_1
    Associated_feature: WBsf643287
      WBsf643288
      WBsf643289
      WBsf656310
      WBsf983664
      WBsf983665
      WBsf1009808
  Experimental_info: RNAi_result: WBRNAi00032838 Inferred_automatically: RNAi_primary
      WBRNAi00002223 Inferred_automatically: RNAi_primary
      WBRNAi00003774 Inferred_automatically: RNAi_primary
      WBRNAi00114793 Inferred_automatically: RNAi_primary
      WBRNAi00048419 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1011247
      Expr1030601
      Expr1152208
      Expr2010914
      Expr2029153
    Drives_construct: WBCnstr00037173
    Construct_product: WBCnstr00037173
    Microarray_results (27)
    Expression_cluster (258)
    Interaction (59)
  Map_info: Map: I Position: -0.057235 Error: 0.008171
    Positive: Positive_clone: F55A12 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00029387
    WBPaper00038491
    WBPaper00042257
    WBPaper00045631
    WBPaper00055090
    WBPaper00059839
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene