WormBase Tree Display for Gene: WBGene00000935

WBGene00000935 SMap: S_parent: Sequence: F56D1
  Identity: Version: 1
    Name: CGC_name: daz-1 Person_evidence: WBPerson634
      Sequence_name: F56D1.7
      Molecular_name: F56D1.7
        F56D1.7.1
        CE27175
      Other_name: CELE_F56D1.7 Accession_evidence: NDB BX284602
      Public_name: daz-1
    DB_info: Database: AceView gene 2F747
        WormQTL gene WBGene00000935
        WormFlux gene WBGene00000935
        NDB locus_tag CELE_F56D1.7
        Panther gene CAEEL|WormBase=WBGene00000935|UniProtKB=Q20870
          family PTHR11176
        NCBI gene 173931
        RefSeq protein NM_062635.5
        SwissProt UniProtAcc Q20870
        TREEFAM TREEFAM_ID TF324396
        UniProt_GCRP UniProtAcc Q20870
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:22 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: daz
    Allele (32)
    Legacy_information: [Sugimoto A] encodes a protein similar to human DAZ (Deleted in Azoospermia), includes a RNP-type RNA-binding motif and a DAZ-family-specific motif, tj3 (deletion allele) is defective in progression of meiosis during oogenesis, spermatogenesis unaffected.
    Strain: WBStrain00033879
    RNASeq_FPKM (74)
    GO_annotation (12)
    Ortholog (36)
    Structured_description: Concise_description: daz-1 encodes a protein containing an RNA recognition motif that is required for the progression of meiosis during oogenesis; DAZ-1 is expressed in the germline, and expression levels peak in the proximal pachytene region; cpb-3(bt17);daz-1(tj3) hermaphrodites have a synthetic phenotype of total sterility and masculinization; DAZ-1 colocalizes with CPB-3 invivo, coimmunoprecipitates with CPB-3, and binds CPB-3 in two-hybrid assays. Paper_evidence: WBPaper00003942
            WBPaper00027619
          Curator_confirmed: WBPerson48
            WBPerson567
          Date_last_updated: 19 Apr 2007 00:00:00
      Automated_description: Predicted to enable mRNA 3'-UTR binding activity and translation activator activity. Predicted to be involved in 3'-UTR-mediated mRNA stabilization and positive regulation of translational initiation. Located in cytoplasm. Expressed in germ line; gonad; and in male. Is an ortholog of several human genes including DAZ1 (deleted in azoospermia 1); DAZ2 (deleted in azoospermia 2); and DAZ3 (deleted in azoospermia 3). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F56D1.7
    Corresponding_transcript: F56D1.7.1
    Other_sequence (103)
    Associated_feature: WBsf987888
      WBsf987889
      WBsf987890
      WBsf987891
      WBsf1012231
  Experimental_info (9)
  Map_info: Map: II Position: -1.40837 Error: 0.030556
    Positive: Positive_clone: F56D1 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4253
        4538
    Pseudo_map_position
  Reference (36)
  Remark: Sequence connection updated to .7 rather than .5 following advice of Danielle Thierry-Mieg. 02/06/12 krb.
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene