WormBase Tree Display for Gene: WBGene00000865
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WBGene00000865 | SMap | S_parent | Sequence | ZC168 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 1 | |||||||
Name | CGC_name | cyb-1 | |||||||
Sequence_name | ZC168.4 | ||||||||
Molecular_name | ZC168.4 | ||||||||
ZC168.4.1 | |||||||||
CE06570 | |||||||||
ZC168.4.2 | |||||||||
Other_name | CELE_ZC168.4 | Accession_evidence | NDB | BX284604 | |||||
Public_name | cyb-1 | ||||||||
DB_info | Database | AceView | gene | 4L501 | |||||
WormQTL | gene | WBGene00000865 | |||||||
WormFlux | gene | WBGene00000865 | |||||||
NDB | locus_tag | CELE_ZC168.4 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00000865|UniProtKB=Q10653 | |||||||
family | PTHR10177 | ||||||||
NCBI | gene | 177965 | |||||||
RefSeq | protein | NM_069586.9 | |||||||
SwissProt | UniProtAcc | Q10653 | |||||||
TREEFAM | TREEFAM_ID | TF101001 | |||||||
UniProt_GCRP | UniProtAcc | Q10653 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:21 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | cyb | ||||||||
Allele (28) | |||||||||
Legacy_information | [C.elegansII] NMK. 72% identity to sea urchin cyclin B. [KB] | ||||||||
Strain | WBStrain00035505 | ||||||||
WBStrain00035506 | |||||||||
WBStrain00054975 | |||||||||
WBStrain00054710 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (20) | |||||||||
Ortholog (45) | |||||||||
Paralog (13) | |||||||||
Structured_description | Concise_description | cyb-1 encodes a cyclin B homolog that appears to be required both for embryogenesis (via maternally encoded CYB-1) and for postembryonic development and fertility (via zygotically encoded CYB-1); removing maternal product in cyb-1(RNAi) embryos causes multiple nuclei, and affected embryos arrest development at an early embryonic stage. | Paper_evidence (2) | ||||||
Curator_confirmed | WBPerson567 | ||||||||
Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
Automated_description | Enables cyclin-dependent protein serine/threonine kinase regulator activity and ubiquitin protein ligase binding activity. Involved in mitotic cell cycle; oocyte maturation; and positive regulation of protein phosphorylation. Located in cytoplasm and nucleus. Expressed in germ cell; male gonad; and oocyte. Human ortholog(s) of this gene implicated in several diseases, including in situ carcinoma; renal cell carcinoma; and reproductive organ cancer (multiple). Is an ortholog of human CCNB1 (cyclin B1). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model | DOID:2871 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1579) | ||||
DOID:4450 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1579) | ||||||
DOID:8719 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1579) | ||||||
DOID:2152 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1579) | ||||||
DOID:10283 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1579) | ||||||
DOID:2526 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1579) | ||||||
DOID:4362 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1579) | ||||||
DOID:1612 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1579) | ||||||
Molecular_info | Corresponding_CDS | ZC168.4 | |||||||
Corresponding_transcript | ZC168.4.1 | ||||||||
ZC168.4.2 | |||||||||
Other_sequence (25) | |||||||||
Associated_feature | WBsf646328 | ||||||||
WBsf655051 | |||||||||
WBsf229031 | |||||||||
WBsf229032 | |||||||||
WBsf229033 | |||||||||
WBsf229034 | |||||||||
Experimental_info | RNAi_result | WBRNAi00085858 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00037964 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00021586 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00058758 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00106163 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00007847 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern (14) | |||||||||
Drives_construct | WBCnstr00001396 | ||||||||
WBCnstr00011275 | |||||||||
WBCnstr00037238 | |||||||||
WBCnstr00041759 | |||||||||
Construct_product | WBCnstr00000443 | ||||||||
WBCnstr00001396 | |||||||||
WBCnstr00007949 | |||||||||
WBCnstr00008139 | |||||||||
WBCnstr00011275 | |||||||||
WBCnstr00037238 | |||||||||
WBCnstr00041759 | |||||||||
Antibody (4) | |||||||||
Microarray_results (24) | |||||||||
Expression_cluster (225) | |||||||||
Interaction (252) | |||||||||
Map_info | Map | IV | Position | 4.6818 | Error | 0.002007 | |||
Positive | Positive_clone | KB#1 | |||||||
ZC168 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||||
Mapping_data | Multi_point | 4245 | |||||||
4322 | |||||||||
Pseudo_map_position | |||||||||
Reference (32) | |||||||||
Remark | Sequence connection from [Xu H, Bennett KL] | ||||||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
Method | Gene |