WormBase Tree Display for Gene: WBGene00000795
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| WBGene00000795 | Evidence | Paper_evidence | WBPaper00005857 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | CD4 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | crn-2 | Person_evidence | WBPerson1606 | |||||
| Sequence_name | CD4.2 | ||||||||
| Molecular_name | CD4.2 | ||||||||
| CD4.2.1 | |||||||||
| CE16950 | |||||||||
| Other_name | CELE_CD4.2 | Accession_evidence | NDB | BX284605 | |||||
| Public_name | crn-2 | ||||||||
| DB_info | Database | AceView | gene | 5G75 | |||||
| WormQTL | gene | WBGene00000795 | |||||||
| WormFlux | gene | WBGene00000795 | |||||||
| NDB | locus_tag | CELE_CD4.2 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00000795|UniProtKB=G5EG18 | |||||||
| family | PTHR10060 | ||||||||
| NCBI | gene | 178945 | |||||||
| RefSeq | protein | NM_072075.8 | |||||||
| TrEMBL | UniProtAcc | G5EG18 | |||||||
| UniProt_GCRP | UniProtAcc | G5EG18 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:21 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | crn | ||||||||
| Allele (27) | |||||||||
| Strain | WBStrain00002311 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (11) | |||||||||
| Contained_in_operon | CEOP5076 | ||||||||
| Ortholog (35) | |||||||||
| Paralog | WBGene00012496 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||||
| WBGene00012562 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00015189 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | crn-2 encodes a cell death-related nuclease, homologous to the magnesium-dependant TatD nuclease of E. coli; CRN-2 is required for normal levels of DNA degradation during apoptosis; crn-2(RNAi) 1.5-fold stage embryos display TUNEL labelling of nuclei that is five-fold higher than that seen in untreated N2 animals; CRN-2 promotes both DNA degradation and cell corpse engulfment, in a partially redundant pathway that includes CRN-3 but is parallel to CPS-6; CRN-2 is predicted to be mitochondrial. | Paper_evidence | WBPaper00004424 | |||||
| WBPaper00005857 | |||||||||
| WBPaper00012801 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Enables DNA nuclease activity. Involved in apoptotic DNA fragmentation and apoptotic cell clearance. Predicted to be located in cytosol. Expressed in head and tail. Is an ortholog of human TATDN1 (TatD DNase domain containing 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | CD4.2 | |||||||
| Corresponding_transcript | CD4.2.1 | ||||||||
| Other_sequence (16) | |||||||||
| Associated_feature | WBsf034306 | ||||||||
| WBsf231773 | |||||||||
| WBsf231774 | |||||||||
| WBsf231775 | |||||||||
| Experimental_info | RNAi_result (13) | ||||||||
| Expr_pattern | Chronogram1629 | ||||||||
| Expr5603 | |||||||||
| Expr5604 | |||||||||
| Expr1025604 | |||||||||
| Expr1030494 | |||||||||
| Expr1147282 | |||||||||
| Expr2010537 | |||||||||
| Expr2028777 | |||||||||
| Drives_construct | WBCnstr00002704 | ||||||||
| WBCnstr00004400 | |||||||||
| WBCnstr00037271 | |||||||||
| Construct_product | WBCnstr00037271 | ||||||||
| Microarray_results (20) | |||||||||
| Expression_cluster (132) | |||||||||
| Interaction (15) | |||||||||
| WBProcess | WBbiopr:00000014 | ||||||||
| WBbiopr:00000103 | |||||||||
| Map_info | Map | V | Position | -1.36243 | Error | 0.005406 | |||
| Positive | Positive_clone | CD4 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00005857 | ||||||||
| WBPaper00006283 | |||||||||
| WBPaper00019408 | |||||||||
| WBPaper00027291 | |||||||||
| WBPaper00028482 | |||||||||
| WBPaper00035429 | |||||||||
| WBPaper00036025 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00041771 | |||||||||
| WBPaper00055090 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
