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WormBase Tree Display for Gene: WBGene00000785

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Name Class

WBGene00000785SMapS_parentSequenceW07B8
IdentityVersion1
NameCGC_namecpr-5
Sequence_nameW07B8.5
Molecular_nameW07B8.5
W07B8.5.1
CE14682
Other_nameCELE_W07B8.5Accession_evidenceNDBBX284605
Public_namecpr-5
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:21WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classcpr
Allele (36)
Legacy_information[C.elegansII] NMK. Encodes protein with significant similarity to proteases of Cathepsin B family (EST cm04d10). [IA]
StrainWBStrain00032501
RNASeq_FPKM (74)
GO_annotation00045998
00045999
00046000
00046001
00046002
00046003
00046004
00107790
00107791
Ortholog (51)
Paralog (28)
Structured_descriptionConcise_descriptioncpr-5 encodes a cysteine protease.Curator_confirmedWBPerson48
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable cysteine-type endopeptidase activity. Predicted to be involved in proteolysis involved in protein catabolic process. Predicted to be located in extracellular space. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease of the nervous system (multiple); carcinoma (multiple); and type 2 diabetes mellitus. Is an ortholog of human CTSB (cathepsin B).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:9351Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2527)
DOID:11054Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2527)
DOID:2671Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2527)
DOID:9352Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2527)
DOID:2377Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2527)
DOID:10941Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2527)
DOID:12842Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2527)
DOID:3068Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2527)
DOID:4914Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2527)
DOID:1612Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2527)
Molecular_infoCorresponding_CDSW07B8.5
Corresponding_transcriptW07B8.5.1
Other_sequence (77)
Associated_featureWBsf652462
WBsf233316
Experimental_infoRNAi_resultWBRNAi00115172Inferred_automaticallyRNAi_primary
WBRNAi00054943Inferred_automaticallyRNAi_primary
Expr_patternExpr742
Expr1028465
Expr1030486
Expr1158478
Expr2010506
Expr2028746
Drives_constructWBCnstr00000639
WBCnstr00037277
Construct_productWBCnstr00037277
Microarray_results (19)
Expression_cluster (342)
Interaction (66)
Map_infoMapVPosition-19.8522Error0.000529
PositivePositive_cloneW02B2
W07B8Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (12)
Remarkdata received 11/94. Distinct from cpr-1.
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene