WormBase Tree Display for Gene: WBGene00000784
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| WBGene00000784 | SMap | S_parent | Sequence | F44C4 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | cpr-4 | |||||||
| Sequence_name | F44C4.3 | ||||||||
| Molecular_name | F44C4.3 | ||||||||
| F44C4.3.1 | |||||||||
| CE07251 | |||||||||
| Other_name | CELE_F44C4.3 | Accession_evidence | NDB | BX284605 | |||||
| Public_name | cpr-4 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:21 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | cpr | ||||||||
| Allele (33) | |||||||||
| Legacy_information | [C.elegansII] NMK. Encodes protein with significant similarity to proteases of Cathepsin B family (EST cm14e3). [IA] | ||||||||
| Strain | WBStrain00033148 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (16) | |||||||||
| Ortholog (44) | |||||||||
| Paralog (28) | |||||||||
| Structured_description | Concise_description | cpr-4 encodes a cathepsin B-like cysteine protease expressed at all life stages. | Paper_evidence | WBPaper00002373 | |||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Enables cysteine-type endopeptidase activity. Involved in cellular response to UV; cellular response to gamma radiation; and proteolysis involved in protein catabolic process. Located in extracellular region. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease of the nervous system (multiple); carcinoma (multiple); and type 2 diabetes mellitus. Is an ortholog of human CTSB (cathepsin B). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:9351 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2527) | ||||
| DOID:11054 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2527) | ||||||
| DOID:2671 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2527) | ||||||
| DOID:9352 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2527) | ||||||
| DOID:2377 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2527) | ||||||
| DOID:10941 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2527) | ||||||
| DOID:12842 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2527) | ||||||
| DOID:3068 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2527) | ||||||
| DOID:4914 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2527) | ||||||
| DOID:1612 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2527) | ||||||
| Molecular_info | Corresponding_CDS | F44C4.3 | |||||||
| Corresponding_transcript | F44C4.3.1 | ||||||||
| Other_sequence (375) | |||||||||
| Associated_feature | WBsf646890 | ||||||||
| WBsf1000314 | |||||||||
| WBsf231894 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00007344 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00115171 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00047258 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr741 | ||||||||
| Expr13281 | |||||||||
| Expr1014351 | |||||||||
| Expr1030485 | |||||||||
| Expr1151114 | |||||||||
| Expr2010505 | |||||||||
| Expr2028745 | |||||||||
| Drives_construct | WBCnstr00037278 | ||||||||
| WBCnstr00039152 | |||||||||
| Construct_product | WBCnstr00037278 | ||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (354) | |||||||||
| Interaction (146) | |||||||||
| Map_info | Map | V | Position | 0.113422 | Error | 0.001009 | |||
| Positive | Positive_clone | F44C4 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| W02B2 | Author_evidence | Larminie CGC | |||||||
| ZK1055 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (15) | |||||||||
| Remark | data received 11/94 | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
