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WormBase Tree Display for Gene: WBGene00000783

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Name Class

WBGene00000783SMapS_parentSequenceCHROMOSOME_V
IdentityVersion1
NameCGC_namecpr-3
Sequence_nameT10H4.12
Molecular_nameT10H4.12
T10H4.12.1
CE27590
Other_nameCELE_T10H4.12Accession_evidenceNDBBX284605
Public_namecpr-3
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:21WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classcpr
Allele (82)
Legacy_information[C.elegansII] NMK. Encodes protein with significant similarity to proteases of Cathepsin B family, (EST cm12b6);50% identity to CPR-1. [IA]
StrainWBStrain00036503
RNASeq_FPKM (74)
GO_annotation00045976
00045977
00045978
00045979
00045980
00045981
00045982
00045983
00107786
00107787
Ortholog (58)
Paralog (28)
Structured_descriptionAutomated_descriptionPredicted to enable cysteine-type endopeptidase activity. Involved in innate immune response. Predicted to be located in extracellular space. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease of the nervous system (multiple); carcinoma (multiple); and type 2 diabetes mellitus. Is an ortholog of human CTSB (cathepsin B).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:9351Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2527)
DOID:11054Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2527)
DOID:2671Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2527)
DOID:9352Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2527)
DOID:2377Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2527)
DOID:10941Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2527)
DOID:12842Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2527)
DOID:3068Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2527)
DOID:4914Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2527)
DOID:1612Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2527)
Molecular_infoCorresponding_CDST10H4.12
Corresponding_CDS_historyT10H4.12:wp51
Corresponding_transcriptT10H4.12.1
Other_sequence (108)
Associated_featureWBsf653441
WBsf235047
WBsf235048
Experimental_infoRNAi_resultWBRNAi00018565Inferred_automaticallyRNAi_primary
WBRNAi00053076Inferred_automaticallyRNAi_primary
WBRNAi00076672Inferred_automaticallyRNAi_primary
WBRNAi00001088Inferred_automaticallyRNAi_primary
WBRNAi00089155Inferred_automaticallyRNAi_primary
WBRNAi00115170Inferred_automaticallyRNAi_primary
WBRNAi00086769Inferred_automaticallyRNAi_primary
WBRNAi00053075Inferred_automaticallyRNAi_primary
Expr_patternExpr740
Expr6666
Expr1012685
Expr1156684
Expr2010504
Expr2028744
Drives_constructWBCnstr00003439
WBCnstr00037279
Construct_productWBCnstr00037279
Microarray_results (19)
Expression_cluster (337)
Interaction (35)
Map_infoMapVPosition7.66653Error0.001313
PositivePositive_cloneCL#034
T10H4Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00002373
WBPaper00021893
WBPaper00028482
WBPaper00031025
WBPaper00038491
WBPaper00055090
WBPaper00059755
WBPaper00065331
WBPaper00065759
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene