WormBase Tree Display for Gene: WBGene00000764
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| WBGene00000764 | Evidence | Paper_evidence | WBPaper00013270 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | T03F1 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | coq-4 | Person_evidence | WBPerson247 | |||||
| Sequence_name | T03F1.2 | ||||||||
| Molecular_name | T03F1.2 | ||||||||
| T03F1.2.1 | |||||||||
| CE40117 | |||||||||
| Other_name | CELE_T03F1.2 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | coq-4 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:21 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | coq | ||||||||
| Allele (14) | |||||||||
| Strain | WBStrain00032044 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (13) | |||||||||
| Contained_in_operon | CEOP1124 | ||||||||
| Ortholog (38) | |||||||||
| Structured_description | Concise_description | coq-4 encodes an ortholog of S. cerevisiae COQ4; while COQ-4 is conservedbetween eukaryotes and bacteria, its biochemical function is unknown; byorthology, COQ-4 is predicted to peripherally associate with the matrixface of the mitochondrial inner membrane, in a complex with COQ-3 (andperhaps COQ-6), and to be required to maintain a steady-state level ofCLK-1/COQ-7 protein; COQ-4 is required for ubiquinone (coenzyme Q9)biosynthesis and for normally short lifespan; coq-4(RNAi) animals havereduced levels of coenzyme Q9 and superoxide, and have abnormally longlifespans. | Paper_evidence | WBPaper00005863 | |||||
| WBPaper00028293 | |||||||||
| WBPaper00028311 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 11 Aug 2006 00:00:00 | ||||||||
| Automated_description | Involved in ubiquinone biosynthetic process. Predicted to be located in mitochondrion. Predicted to be extrinsic component of mitochondrial inner membrane. Human ortholog(s) of this gene implicated in primary coenzyme Q10 deficiency 7. Is an ortholog of human COQ4 (coenzyme Q4). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0070244 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:19693) | ||||
| Molecular_info | Corresponding_CDS | T03F1.2 | |||||||
| Corresponding_CDS_history | T03F1.2:wp156 | ||||||||
| Corresponding_transcript | T03F1.2.1 | ||||||||
| Other_sequence (52) | |||||||||
| Associated_feature | WBsf217450 | ||||||||
| WBsf217451 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00022973 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00004117 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00052281 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1014018 | ||||||||
| Expr1030469 | |||||||||
| Expr1155913 | |||||||||
| Expr2010464 | |||||||||
| Expr2028704 | |||||||||
| Drives_construct | WBCnstr00037295 | ||||||||
| Construct_product | WBCnstr00037295 | ||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (77) | |||||||||
| Interaction (44) | |||||||||
| Map_info | Map | I | Position | -1.96255 | Error | 0.004014 | |||
| Positive | Positive_clone | T03F1 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 5230 | |||||||
| 4309 | |||||||||
| 4973 | |||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00005863 | ||||||||
| WBPaper00006360 | |||||||||
| WBPaper00011299 | |||||||||
| WBPaper00025408 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00055090 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
