WormBase Tree Display for Gene: WBGene00000761
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| WBGene00000761 | Evidence | Paper_evidence | WBPaper00013270 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | C24A11 | ||||||
| Identity | Version | 2 | |||||||
| Name | CGC_name | coq-1 | Person_evidence | WBPerson247 | |||||
| Sequence_name | C24A11.9 | ||||||||
| Molecular_name | C24A11.9 | ||||||||
| C24A11.9.1 | |||||||||
| CE29183 | |||||||||
| Other_name | tag-134 | CGC_data_submission | |||||||
| let-370 | Person_evidence | WBPerson533 | |||||||
| CELE_C24A11.9 | Accession_evidence | NDB | BX284601 | ||||||
| Public_name | coq-1 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:21 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 04 Mar 2015 11:37:44 | WBPerson2970 | Event | Acquires_merge | WBGene00002590 | ||||
| Name_change | Other_name | let-370 | |||||||
| Acquires_merge | WBGene00002590 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | coq | ||||||||
| Allele (26) | |||||||||
| Legacy_information | [McDowall JS] Sterile adult | ||||||||
| [C.elegansII] h128 : sterile adult or Mel with larval lethality. OA1: h210. [Howell et al. 1987; KR] | |||||||||
| Strain | WBStrain00023687 | ||||||||
| WBStrain00035805 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (13) | |||||||||
| Contained_in_operon | CEOP1248 | ||||||||
| Ortholog (35) | |||||||||
| Structured_description | Concise_description | coq-1 encodes a putative hexaprenyl pyrophosphate synthetase,orthologous to S. cerevisiae COQ1; COQ-1 is required for ubiquinone(coenzyme Q9) biosynthesis and for normally short lifespan; coq-1mutants have slowed pharyngeal pumping, and eventually arrest asparalysed larvae before dying; coq-1(RNAi) animals have reduced levelsof coenzyme Q9 and superoxide, and have abnormally long lifespans; coq-1mutants are not rescued by dietary coenzyme Q. | Paper_evidence | WBPaper00005863 | |||||
| WBPaper00028317 | |||||||||
| WBPaper00028394 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 26 Oct 2006 00:00:00 | ||||||||
| Automated_description | Predicted to enable prenyltransferase activity. Involved in ubiquinone biosynthetic process. Predicted to be extrinsic component of mitochondrial inner membrane. Predicted to be part of transferase complex. Human ortholog(s) of this gene implicated in primary coenzyme Q10 deficiency 2. Is an ortholog of human PDSS1 (decaprenyl diphosphate synthase subunit 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0070239 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:17759) | ||||
| Molecular_info | Corresponding_CDS | C24A11.9 | |||||||
| Corresponding_transcript | C24A11.9.1 | ||||||||
| Other_sequence (25) | |||||||||
| Associated_feature | WBsf716921 | ||||||||
| WBsf981014 | |||||||||
| WBsf983687 | |||||||||
| WBsf983688 | |||||||||
| WBsf983689 | |||||||||
| WBsf1009823 | |||||||||
| WBsf1009824 | |||||||||
| WBsf219422 | |||||||||
| WBsf219423 | |||||||||
| Experimental_info | RNAi_result (36) | ||||||||
| Expr_pattern | Expr13707 | ||||||||
| Expr1019532 | |||||||||
| Expr1030467 | |||||||||
| Expr1145088 | |||||||||
| Expr2010461 | |||||||||
| Expr2028701 | |||||||||
| Drives_construct | WBCnstr00037297 | ||||||||
| WBCnstr00039949 | |||||||||
| Construct_product | WBCnstr00037297 | ||||||||
| WBCnstr00039949 | |||||||||
| Microarray_results (22) | |||||||||
| Expression_cluster (134) | |||||||||
| Interaction (26) | |||||||||
| Map_info | Map | I | Position | -0.020987 | Error | 0.00265 | |||
| Representative_for | WBGene00002797 | ||||||||
| Positive | Positive_clone | C24A11 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Negative | Outside_rearr | hDf28 | |||||||
| Negative_clone | C12H4 | ||||||||
| C24H1 | |||||||||
| C28A7 | |||||||||
| C30A6 | |||||||||
| F40D12 | |||||||||
| M01A10 | |||||||||
| M01E11 | |||||||||
| Mapping_data | 2_point | 2537 | |||||||
| Multi_point | 4234 | ||||||||
| 1023 | |||||||||
| Pos_neg_data | 2571 | ||||||||
| 2710 | |||||||||
| 4546 | |||||||||
| 4547 | |||||||||
| 5327 | |||||||||
| 5374 | |||||||||
| 3777 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (19) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| [McDowall JS] Extrachromosomal arrays containing three cosmids generated, then manipulated genetically. | |||||||||
| Method | Gene |
