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WormBase Tree Display for Gene: WBGene00000539

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Name Class

WBGene00000539EvidenceCGC_data_submission
SMapS_parentSequenceF07B10
IdentityVersion1
NameCGC_namecln-3.1
Sequence_nameF07B10.1
Molecular_nameF07B10.1a
F07B10.1a.1
CE09198
F07B10.1b
CE46158
F07B10.1b.1
Other_nameCELE_F07B10.1Accession_evidenceNDBBX284605
Public_namecln-3.1
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:21WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_info (9)
Disease_infoExperimental_modelDOID:14503Homo sapiensPaper_evidenceWBPaper00027030
Accession_evidenceOMIM204200
Curator_confirmedWBPerson324
Date_last_updated08 May 2017 00:00:00
Potential_modelDOID:0110731Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2074)
Models_disease_assertedWBDOannot00000119
WBDOannot00000314
Molecular_infoCorresponding_CDSF07B10.1a
F07B10.1b
Corresponding_transcriptF07B10.1a.1
F07B10.1b.1
Other_sequence (13)
Associated_featureWBsf234521
Experimental_infoRNAi_resultWBRNAi00043854Inferred_automaticallyRNAi_primary
WBRNAi00030592Inferred_automaticallyRNAi_primary
Expr_patternChronogram53
Expr3817
Expr3818
Expr3819
Expr5669
Expr1023637
Expr1147829
Expr2010240
Expr2028482
Drives_constructWBCnstr00003732
WBCnstr00011674
WBCnstr00037464
Construct_productWBCnstr00037464
Microarray_results (19)
Expression_cluster (180)
InteractionWBInteraction000122588
WBInteraction000133974
WBInteraction000133975
WBInteraction000285465
WBInteraction000319652
WBInteraction000391919
WBInteraction000415645
Map_infoMapVPosition3.03495Error0.0019
PositivePositive_cloneF01B10
F07B10Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point4225
4365
4855
4822
Pseudo_map_position
Reference (11)
Remark[Sara E Mole] Three C. elegans genes are equally similar to the human gene CLN3 which causes juvenile neuronal ceroid lipofuscinosis (NCL) or Batten disease. There is at least one similar gene in over 20 eukaryotic species, including S. cerevisiae, S.pombe, D. melanogaster. No other completely sequenced genome has more than one CLN3 homologue. All three cln-3 genes in C. elegans are trancribed and accession numbers have been applied for. In human there are up to 8 NCL genes named CLN-8. CLN1 also has one homologue in C. elegans. CLN1 encodes the enzyme palmitoyl protein thioesterase 1 (PPT1).
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene